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Waters SPE cartridge equivalent - Oasis HLB, Sep-pak C18 & More


GL Sciences Equivalent for Waters SPE cartridges

Waters SPE cartridge equivalent InertSep

InertSep SPE columns from GL Sciences are designed for easy and cost-effective preparation of laboratory samples. With a wide variety of polymer and silica-based sorbents, InertSep SPE columns allows you to prepare samples with the exact separation mode and chemistry needed.



Waters SPE cartridge equivalent InertSep

Available in multiple formats:

Cartridge SPE column


Large-size Cartridge SPE column

Large-size cartridge

Luer Device type SPE column

Luer Device Type

96-well plate SPE column

96-Well Plate

For effective extraction of a wide variety of compounds from non-polar to high-polarity using a hydrophilic-lipophilic balanced phase 

InertSep HLB

Recommended GL Sciences equivalent for Waters Oasis HLB

InertSep HLB is a composite polymer solid phase of N-containing vinyl polymer and styrene divinylbenzene. By optimizing the balance between hydrophobicity and hydrophilicity with a unique synthetic technology, InertSep HLB can retain and elute compounds with a wide range of polarities.

Available in several particle sizes for different flow requirements:

  InertSep HLB InertSep HLB FF
Average particle diameter (μm) 30 60
Surface area (m2/g) 720
Pore volume (mL/g) 1.3
Fine pore size (nm) 7
pH range of use 1-14

High-efficiency reversed phase extraction with a highly end-capped C18 phase

InertSep C18

Recommended GL Sciences equivalent for Waters Sep-Pak tC18

Waters Sep-Pak tC18 equivalent InertSep C18

InertSep C18 is a silica-based sorbent modified with C18 for non-polar interactions. With our high-level end-capping technology, cation exchange by interaction with the residual silanol groups is suppressed, which reduces adsorption of basic compounds. This sorbent is suitable for removing lipid in simultaneous analysis of pesticide residues in agricultural products.

Available in several particle sizes for different flow requirements.

  InertSep C18 InertSep C18 FF
Average particle diameter (μm) 60 120
Carbon Load (%) 19
Surface area (m2/g) 450
Pore volume (mL/g) 0.7
Fine pore size (nm) 6
pH range of use 2-8

2x4 Method Phases

GL Sciences provides several mixed-mode SPE sorbents for use with the 2x4 Method. GL Sciences SPE phases feature stable holding power, excellent permeability and selection of particle sizes including large diameters with high flow-rate ideal for sample pre-treatment. 

  InertSep MCX FF InertSep MAX FF InertSep WCX FF InertSep WAX FF
Recommended equivalent to Oasis MCX Oasis MAX Oasis WCX Oasis WAX
Functional group ―SO3- ―N-(CH3)3 ―COO- ―NR2
  Learn More Learn More Learn More Learn More
Average particle diameter (μm) 70
Surface area (m2/g)  480
Pore volume (mL/g) 1.1
Fine pore size (nm) 9
pH range of use 1-14
Ion exchange capacity (meq/g) 1.2 0.3 1.2 0.7

Complete list of InertSep equivalent phases for Waters SPE columns

Waters Base Gel Mode InertSep
Oasis HLB
Polymer based
Reversed Phase
InertSep HLB
Oasis HLB InertSep PLS-3
Oasis HLB InertSep Pharma
Sep-Pak PS-2 InertSep PLS-2
Oasis MCX
Ion Exchange
InertSep MCX
Oasis WCX InertSep WCX
Oasis MAX InertSep MAX
Oasis WAX InertSep WAX
Sep-Pak tC18
Silica based
Reversed Phase
InertSep C18
Sep-Pak C18 InertSep C18-B
Sep-Pak C8 InertSep C8
Sep-Pak tC2 InertSep C2
Sep-Pak CN
Normal Phase
InertSep CN
Sep-Pak Diol InertSep 2OH
Sep-Pak Silica InertSep SI
AccellPlus CM
Ion Exchange
InertSep CBA
Sep-Pak NH2 InertSep NH2
Sep-Pak PSA InertSep PSA
AccellPlus QMA InertSep SAX
Sep-Pak Alumina-A
InertSep AL-A
Sep-Pak Alumina-N InertSep AL-N
Sep-Pak Alumina-B InertSep AL-B
Sep-Pak Florisil InertSep FL
Sep-Pak AC-2
InertSep AC
Sep-Pak DRY InertSep DRY
Sep-Pak Carbon/NH2 InertSep GC/NH2
Sep-Pak DNPH InertSep DNPH
Sirocco FastRemover for Protein
Ostro FastRemover for Phospholipid

Find The Right Column For Your Application

Thousands of applications notes available. Search by compound, category, phase and more.  

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