Inertsil ODS-4 delivers the same extreme inertness to any type of compounds just like InertSustain C18 along with unprecedented stability under 100 % aqueous mobile phases for qualitative and quantitative analysis. However, as the base silica gel and carbon loading are different on Inertsil ODS-4, differences in selectivity can be observed for certain analytes.

Generally, silica based columns are mechanically stable and provide high efficiencies, however, they cannot be used under alkaline conditions and their residual silanol groups tend to adsorb organic bases. InertSustain C18 employs a radically new type of silica, in which the surface of the silica is uniquely modified, enabling precise control of the silica properties.

InertSustain C18 inherits the advantages of all the current Inertsil HPLC columns (e.g., extremely low operating back pressure, superior inertness to typically any analytes, high efficiency and compatibility with a wide range of solvents), but now can be used for wide pH analysis with consistent performance from column to column and lot to lot.

Benefits
• High Inertness • Extremely Low Operating Back Pressure • Long Column Lifetime • pH Range from 1 ～ 10 • Reliable Reproducibility

Inertsil ODS-3 is still GL Sciences’ most popular phase and continues to be used widely and reliably for long established methods in pharmaceutical, and contract research labs. Inertsil ODS-3 has a relatively strong retentivity compared to commercially available ODS columns. In addition, the introduction of higher surface area silica provide high preparative loading capacity without sacrificing peak shape.