Inertsil ODS-4 is highly inert ODS column as well as InertSustain C18. However, as the base Silica gel and carbon load are different, their selectivities show some differences according to the characteristics of the analytes.

Inertsil ODS-4 was developed as a more inert alternative to Inertsil ODS-3 by applying upgraded deactivating techniques.

Benefits

• Perfect End-capping technique
• Intensive elimination of trace metals has been acheevedon the silica gel surface
• Extreme durability to acidic mobile phase conditions
• High stability to 100% aqueous mobile phase conditions

Generally, silica based columns are mechanically stable and provide high efficiencies, however, they cannot be used under alkaline conditions and their residual silanol groups tend to adsorb organic bases. InertSustain C18 employs a radically new type of silica, in which the surface of the silica is uniquely modified, enabling precise control of the silica properties.

InertSustain C18 inherits the advantages of all the current Inertsil HPLC columns (e.g., extremely low operating back pressure, superior inertness to typically any analytes, high efficiency and compatibility with a wide range of solvents), but now can be used for wide pH analysis with consistent performance from column to column and lot to lot.

Benefits

• High Inertness
• Extremely Low Operating Back Pressure
• Long Column Lifetime
• pH Range from 1 ～ 10
• Reliable Reproducibility

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Inertsil ODS-3 is still GL Sciences’ most popular phase and continues to be used widely and reliably for long established methods in pharmaceutical, and contract research labs.

Benefits

• Virtually perfect peak shape for most bases and acids
• Predictable selectivity with very low operating pressure making this ideal for fast/LC, UPLC, and LC/MS
• Exceptional physical and chemical durability provides long column life
• Vast database of chromatographic applications available to assist in method development