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InertSustain AQ-C18 HPLC Columns

Brand: InertSustain
InertSustain AQ-C18 columns are designed to achieve strong retention for highly polar compounds, which is the most challenging goals in developing reversed phase methods. The optimization of bonding of the C18 groups at equal distance to the silica gel enable InertSustain AQ-C18 columns to offer significant retention for highly polar compounds even under water rich mobile phases.

Benefits

• Exceptional retention for highly polar compounds (hydrophilic)
• Highly inert packing material results in less tailing of peaks for virtually any type of analytes
• Extreme resistance to low and high pH mobile phases
• Reliable Reproducibility, performance & quality
• Endlessly reproducible from column-to-column and batch-to-batch

Overview

Physical Properties

  • Base Material : High Purity ES Silica Gel
  • Particle Size : 1.9 μm, 3 μm, 5 μm
  • Surface Area : 350 m2/g
  • Pore Size : 100 Å (10 nm)
  • Pore Volume : 0.85 mL/g
  • Functional Group : Octadecyl
  • End-capping : Yes
  • Carbon Loading : 13%
  • USP Code : L1, L96
  • pH Range : 1 - 10
InertSustain AQ-C18 HPLC Columns Functional Group

 

As illustrated in the following plot, InertSustain AQ-C18 provided exceptional retention for highly polar compounds even under water rich mobile phases without dewetting or phase collapse.

Retention Properties of InertSustain AQ-C18 columns

 

InertSustain AQ-C18 HPLC Columns Retention Properties of InertSustain AQ-C18

InertSustain AQ-C18 columns provided strong retention for all basic, neutral and acidic compounds under 100% water mobile phase

 

InertSustain AQ-C18 HPLC Columns compounds

 

Highly Polar Compound Retention with 100% Aqueous Mobile Phases

 

It is indeed difficult to retain highly polar samples by reversed phase mode as the polar samples tend to elute near the t0 (void volume) with water rich mobile phases. On the other hand, polar embedded C18 columns or C18 columns with hydrophilic endcapping are available in the market for retaining highly polar compounds. However, they often show tailing or poor peak shapes due to the secondary interaction from their embedded functional groups.

InertSustain AQ-C18 columns not only provide strong retention for highly polar compounds, but also delivery symmetric peak shapes for virtually any type of analytes.

 

InertSustain AQ-C18 HPLC Columns Highly Polar Compound Retention with 100% Aqueous Mobile Phases

 

Retentivity Under 20% Organic Solvent

 

As shown below, InertSustain AQ-C18 columns delivered stronger retention of catechin sample even under 20% organic solvent mobile phase with exceptional peak shapes, while competitive column brand failed. Furthermore, InertSustain AQ-C18 can prevent the co-elution between the targeted polar analytes and solvent peaks or sample matrices due to its enhanced retentivity.

 

InertSustain AQ-C18 HPLC Columns Retentivity Under 20% Organic Solvent

 

Applications

 

View Catalog Here

 

Analytical Columns

 

InertSustain AQ-C18 HPLC Columns SKU list 1 InertSustain AQ-C18 HPLC Columns SKU list 2

Cartridge Guard Columns

 

InertSustain AQ-C18 HPLC Columns SKU list 3 

Products

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264 Items
150 mm
3.0 mm
3 µm HP
$840.00
30 mm
3.0 mm
3 µm HP
$700.00
100 mm
4.6 mm
3 µm HP
$760.00
50 mm
4.6 mm
3 µm HP
$700.00
75 mm
3.0 mm
3 µm HP
$760.00
30 mm
4.6 mm
3 µm HP
$700.00
250 mm
3.0 mm
3 µm HP
$860.00
75 mm
4.6 mm
3 µm HP
$760.00
50 mm
3.0 mm
3 µm HP
$700.00
100 mm
3.0 mm
3 µm HP
$760.00

Applications

There are application notes for InertSustain AQ-C18 HPLC Columns.

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