Inertsil C8-3 provides pure reverse phase characteristics that are critical to resolving highly polar compounds like acidic and basic pharmaceuticals. The near perfect C8 ( octyl ) phase and end-capping coverage on this material results in symmetric, narrow peaks for even the most polar compounds while using simple eluents like aqueous MeCN or MeOH. The need for ion-pair and competing-amine eluent modifiers that are necessary with many other reverse phase columns is eliminated on Inertsil 3-series phases.
The Inertsil 3-series represents a major advance in performance over the original Inertsil 2-Series. Inertsil 3-Series phases, including ODS-4, ODS-3, ODS-3V, ODS-SPRINT , ODS-P, ODS-EP, Ph-3, CN-3, NH2, Diol, and SIL-100Å, are based on a purer, higher surface area silica which is specially manufactured to provide maximum bonded phase coverage. The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure.
GL Sciences has compiled a vast collection of chromatographic applications data on C8-3 and their other phases which can assist you in method development.
By choosing Inertsil C8-3, you can be assured that you are using one of the most trusted, popular, and enduring HPLC columns in the history of HPLC.