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Supelco SPE cartridge equivalent - Supel-Select, Disovery, Supelclean & More


GL Sciences Equivalent for Supelco SPE cartridges

Supelco SPE cartridge equivalent InertSep

InertSep SPE columns from GL Sciences are designed for easy and cost-effective preparation of laboratory samples. With a wide variety of polymer and silica-based sorbents, InertSep SPE columns allows you to prepare samples with the exact separation mode and chemistry needed.



Supelco SPE cartridge equivalent InertSep

Available in multiple formats:

Cartridge SPE column


Large-size Cartridge SPE column

Large-size cartridge

Luer Device type SPE column

Luer Device Type

96-well plate SPE column

96-Well Plate


For effective extraction of a wide variety of compounds from non-polar to high-polarity using a hydrophilic-lipophilic balanced phase 

InertSep HLB

Recommended GL Sciences equivalent for Supelco Supel-Select HLB

Supelco Supel-Select HLB equivalent InertSep HLB

InertSep HLB is a composite polymer solid phase of N-containing vinyl polymer and styrene divinylbenzene. By optimizing the balance between hydrophobicity and hydrophilicity with a unique synthetic technology, InertSep HLB can retain and elute compounds with a wide range of polarities.

Available in several particle sizes for different flow requirements.

 InertSep HLBInertSep HLB FF
Average particle diameter (μm)3060
Surface area (m2/g)720
Pore volume (mL/g)1.3
Fine pore size (nm)7
pH range of use1-14

High-efficiency reversed phase extraction with a highly end-capped C18 phase

InertSep C18

Supelco equivalent InertSep C18

InertSep C18 is a silica-based sorbent modified with C18 for non-polar interactions. With our high-level end-capping technology, cation exchange by interaction with the residual silanol groups is suppressed, which reduces adsorption of basic compounds. This sorbent is suitable for removing lipid in simultaneous analysis of pesticide residues in agricultural products.

Available in several particle sizes for different flow requirements.

 InertSep C18InertSep C18 FF
Average particle diameter (μm)60120
Carbon Load (%)19
Surface area (m2/g)450
Pore volume (mL/g)0.7
Fine pore size (nm)6
pH range of use2-8

2x4 Method Phases

GL Sciences provides several mixed-mode SPE sorbents for use with the 2x4 Method. GL Sciences SPE phases feature stable holding power, excellent permeability and selection of particle sizes including large diameters with high flow-rate ideal for sample pre-treatment. 

 InertSep MCX FFInertSep MAX FFInertSep WCX FFInertSep WAX FF
Recommended equivalent to Supel-Select SCX Supel-Select SAX  
Functional group―SO3-―N-(CH3)3―COO-―NR2
 Learn MoreLearn MoreLearn MoreLearn More
Average particle diameter (μm)70
Surface area (m2/g) 480
Pore volume (mL/g)1.1
Fine pore size (nm)9
pH range of use1-14
Ion exchange capacity (meq/g)

Complete list of InertSep equivalent phases for Supelco SPE columns

SupelcoBase GelModeInertSep
Supel-Select HLB
Polymer based
Reversed Phase
InertSep HLB
Supel-Select HLB InertSep PLS-3
Supel-Select HLB InertSep Pharma
 EZ Cartridge RP-1
Supelclean ENVI-Chrom PInertSep PLS-2
Supel-Select SCX
Ion Exchange
InertSep MCX
 InertSep WCX
Supel-Select SAXInertSep MAX
 InertSep WAX
Silica based
Reversed Phase
InertSep C18
Discovery DSC-18Lt InertSep C18-B
Discovery DSC-18 InertSep C18-C
Discovery DSC-8, Supelclean Envi-8, Supelclean LC-8InertSep C8
 InertSep C2
 InertSep CH
Supelclean ENVI-PH InertSep PH
Supelclean ENVI-CN, Supelclean LC-CN
Normal Phase
InertSep CN
Supelclean LC-DIOL InertSep 2OH
Supelclean LC-Si InertSep SI
Supelclean LC-WCX
Ion Exchange
InertSep CBA
Supelclean LC-SCX InertSep PRS
 InertSep SCX
 InertSep SCX-2
Supelclean LC-NH2 InertSep NH2
Supelclean PSA InertSep PSA
Supelclean LC-SAX InertSep SAX
 InertSep SAX-2
Supelclean LC-Almina A
InertSep AL-A
Supelclean LC-Almina N InertSep AL-N
Supelclean LC-Almina B InertSep AL-B
Supelclean LC-Florisil InertSep FL
Supelclean ENVI-Florisil InertSep FL-PR
InertSep AC
Supelclean ENVI-Carb InertSep GC
 InertSep DRY
Extrelut NT InertSep K-solute
Supelclean Carb-II/PSA InertSep GC/PSA
Supel Sphere Carbon/NH2 InertSep GC/NH2
Supelclean Carb-II/SAX/PSA InertSep GC/SAX/PSA
Supelclean SAX/PSA InertSep SAX/PSA
 InertSep DNPH
HybridSPE Phospholipid Phospholipid Remover
 FastRemover MF (0.2um filter)
96-Well Protein Precipitation Filter plate FastRemover for Protein
HybridSPE Phospholipid FastRemover for Phospholipid
 InertSep PCB
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