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Silicycle SPE cartridge equivalent - SiliaPrepX, SiliaPrep & More


GL Sciences Equivalent for Silicycle SPE cartridges

Silicycle SPE cartridge equivalent InertSep

InertSep SPE columns from GL Sciences are designed for easy and cost-effective preparation of laboratory samples. With a wide variety of polymer and silica-based sorbents, InertSep SPE columns allows you to prepare samples with the exact separation mode and chemistry needed.



Silicycle SPE cartridge equivalent InertSep

Available in multiple formats:

Cartridge SPE column


Large-size Cartridge SPE column

Large-size cartridge

Luer Device type SPE column

Luer Device Type

96-well plate SPE column

96-Well Plate


For effective extraction of a wide variety of compounds from non-polar to high-polarity using a hydrophilic-lipophilic balanced phase 

InertSep HLB

Recommended GL Sciences equivalent for Silicycle SiliaPrepX HLB

Silicycle SiliaPrepX equivalent InertSep HLB

InertSep HLB is a composite polymer solid phase of N-containing vinyl polymer and styrene divinylbenzene. By optimizing the balance between hydrophobicity and hydrophilicity with a unique synthetic technology, InertSep HLB can retain and elute compounds with a wide range of polarities.

Available in several particle sizes for different flow requirements.

 InertSep HLBInertSep HLB FF
Average particle diameter (μm)3060
Surface area (m2/g)720
Pore volume (mL/g)1.3
Fine pore size (nm)7
pH range of use1-14

High-efficiency reversed phase extraction with a highly end-capped C18 phase

InertSep C18

Recommended GL Sciences equivalent for Silicycle SiliaPrep C18

Silicycle SiliaPrep C18 equivalent InertSep C18

InertSep C18 is a silica-based sorbent modified with C18 for non-polar interactions. With our high-level end-capping technology, cation exchange by interaction with the residual silanol groups is suppressed, which reduces adsorption of basic compounds. This sorbent is suitable for removing lipid in simultaneous analysis of pesticide residues in agricultural products.

Available in several particle sizes for different flow requirements.

 InertSep C18InertSep C18 FF
Average particle diameter (μm)60120
Carbon Load (%)19
Surface area (m2/g)450
Pore volume (mL/g)0.7
Fine pore size (nm)6
pH range of use2-8

2x4 Method Phases

GL Sciences provides several mixed-mode SPE sorbents for use with the 2x4 Method. GL Sciences SPE phases feature stable holding power, excellent permeability and selection of particle sizes including large diameters with high flow-rate ideal for sample pre-treatment. 

 InertSep MCX FFInertSep MAX FFInertSep WCX FFInertSep WAX FF
Recommended equivalent to SiliaPrepX SCX SiliaPrepX SAX SiliaPrepX WCXSiliaPrepX WAX
Functional group―SO3-―N-(CH3)3―COO-―NR2
 Learn MoreLearn MoreLearn MoreLearn More
Average particle diameter (μm)70
Surface area (m2/g) 480
Pore volume (mL/g)1.1
Fine pore size (nm)9
pH range of use1-14
Ion exchange capacity (meq/g)

Complete list of InertSep equivalent phases for Silicycle SPE columns

SilicycleBase GelModeInertSep
SiliaPrepX HLB
Polymer based
Reversed Phase
InertSep HLB
SiliaPrepX HLBInertSep PLS-3
SiliaPrepX HLBInertSep Pharma
 EZ Cartridge RP-1
SiliaPrepX DVBInertSep PLS-2
SiliaPrepX SCX
Ion Exchange
InertSep MCX
SiliaPrepX WCXInertSep WCX
SiliaPrepX SAXInertSep MAX
SiliaPrepX WAXInertSep WAX
SiliaPrep C18
Silica based
Reversed Phase
InertSep C18
 InertSep C18-B
SiliaPrep C18 necInertSep C18-C
SiliaPrep C8InertSep C8
SiliaPrep C2InertSep C2
SiliaPrep CyclohexylInertSep CH
SiliaPrep Phenyl (PH)InertSep PH
SiliaPrep Cyano
Normal Phase
InertSep CN
SiliaPrep Diol necInertSep 2OH
SiliaPrep SilicaInertSep SI
SiliaPrep WCX
Ion Exchange
InertSep CBA
SiliaPrep Prolylsulfonic Acid (SCX-2)InertSep PRS
SiliaPrep SCXInertSep SCX
 InertSep SCX-2
 InertSep NH2
 InertSep PSA
SiliaPrep SAXInertSep SAX
 InertSep SAX-2
InertSep AL-A
 InertSep AL-N
 InertSep AL-B
 InertSep FL
 InertSep FL-PR
InertSep AC
 InertSep GC
 InertSep DRY
 InertSep K-solute
 InertSep GC/PSA
 InertSep GC/NH2
 InertSep GC/SAX/PSA
 InertSep SAX/PSA
 InertSep DNPH
SiliaPrep TiO2, ZrO2, TiO2/ZrO2Phospholipid Remover
 FastRemover MF (0.2um filter)
 FastRemover for Protein
SiliaPrep TiO2, ZrO2, TiO2/ZrO2FastRemover for Phospholipid
 InertSep PCB
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