- HPLC Columns
- Close Menu ×
- C18 Columns
- Core-shell Columns
- C8 & C4 HPLC Columns
- HILIC HPLC Columns
- PFP & Phenyl HPLC Columns
- Bioseparation LC columns
- SEC HPLC Columns
- All HPLC Columns
- InertSustain C18 First choice for ultra-high inertness and high durability, delivering superior peak shapes with low back pressure.
- Inertsil ODS-3 Most popular C18, trusted for long-established methods, offering strong retentivity and high loading capacity.
- InertSustain AQ-C18 First choice for high-polarity compounds, delivering strong retention even under 100% aqueous mobile phases.
- Inertsil ODS-3V Validated version of ODS-3, designed for GLP/GMP compliance, ensuring batch-to-batch consistency.
- InertSustainSwift C18 Ultra-inert, fast-separation C18 for high-throughput LC-MS and LC-MS/MS with superior peak symmetry.
- InertSustain AX-C18 Mixed-mode C18 with anion exchange for strong retention of highly polar acidic compounds without ion-pairing.
- All C18 Columns visible-xs
- InertCore Biphenyl Core-shell biphenyl for UHPLC/HPLC with superior π-π selectivity and strong retention of aromatic compounds.
- InertCore C8 Core-shell C8 for UHPLC/HPLC with moderate hydrophobicity, enabling fast, efficient, reproducible separations.
- InertCore Plus C18 Core-shell C18 for UHPLC/HPLC with superior reproducibility, durability, and sharp peaks.
- InertSustain C8 Ultra-inert C8 column for rapid analysis of hydrophobic compounds with symmetric peaks across a wide pH range.
- Inertsil C8 Ultra-pure silica C8 column for rapid analysis of hydrophobic compounds, ideal for legacy methods.
- InertSustainSwift C8 Ultra-inert C8 column for low-polarity analytes, peptides, and oligonucleotides with optimized 200Å pore size.
- Inertsil C8-3 Strong retentivity, very inert, and low back pressure, based on the same silica and bonding as Inertsil ODS-3.
- Inertsil WP 300 Wide-pore C8 column for rapid, high-resolution separation of proteins and peptides with sharper peaks.
- Inertsil C4 Low-retentivity C4 column for rapid analysis of highly hydrophobic compounds like fat-soluble vitamins.
- All C8 & C4 Columns visible-xs
- InertSustain Amide First choice for HILIC mode, offering the strongest retention of polar compounds with superior stability in water-rich conditions.
- Inertsil HILIC Diol-bonded HILIC column for excellent peak shape and strong retention of highly polar basic compounds.
- InertSustain NH2 First choice for sugar analysis, offering superior stability, reproducibility, and compatibility with weakly acidic eluents.
- Inertsil NH2 Aminopropyl column for sugar analysis, highly retentive in normal phase with superior stability and reproducibility.
- ProteoSil HILIC Bioseparation-focused HILIC column, excelling in hydrophilic compound, peptide, glycan, and oligonucleotide analysis.
- All HILIC Columns visible-xs
- InertSustain PFP A pentafluorophenyl-modified column designed for enhanced separation of structurally similar compounds through multiple retention mechanisms, including π-π, dipole, and hydrogen bonding interactions.
- InertSustain Phenyl A directly bonded phenyl group gives the InertSustain Phenyl column unique reversed-phase selectivity, ideal for separating polar compounds and structural isomers via π-π and hydrogen bonding interactions.
- InertSustain Phenylhexyl A phenylhexyl-bonded column that offers complementary selectivity to traditional alkyl-chain columns, providing high inertness, reproducibility, and low back pressure.
Get the Right Column for Your Compound — InstantlyWhat compound are you analyzing? - Sample Preparation
- Close Menu ×
- SPE Cartridges & Columns
- Spin Columns
- Proteomics Products
- InertSep QuEChERS kit
- Cleanup/Separating Bulks
- SPE Manifolds
- ALL Sample Preparation
- InertSep C18 Silica sorbent with high end-capping, ideal for lipid removal & pesticide residue analysis.
- InertSep C18-ENV C18 sorbent with low end-capping, optimized for water analysis & anionic surfactant removal.
- InertSep HLB Versatile SPE column for extracting non-polar to highly polar compounds, with a wide pH range (1-14).
- InertSep C8 Silica sorbent with octyl groups, offering weaker retention than C18 for highly retained compounds.
- InertSep SCX Silica-based SPE column with strong cation exchange and non-polar interactions for enhanced retention.
- InertSep SAX Monofunctional C18 sorbent with medium end-capping, allowing secondary interactions for versatile use.
- All SPE Cartridges & Columns visible-xs
- MonoSpin C18 High-permeability spin column for peptide desalting, drug extraction, and fast biological sample preparation.
- MonoSpin ProA Fast Protein A spin column for high-purity IgG antibody purification with >90% recovery.
- MonoSpin C18-CX Mixed-mode spin column with C18 and cation exchange for enhanced basic drug recovery.
- MonoSpin Phospholipid TiO₂/ZrO₂-coated spin column for efficient phospholipid removal and matrix effect reduction.
- MonoSpin SAX Strong anion exchange spin column for fast extraction of acidic drugs with high recovery.
- MonoSpin TiO TiO₂ spin column for phospholipid removal and organophosphorus pesticide purification.
- All Spin Columns visible-xs
- Exosome Purification
- Desalting
- Digestion
- Fractionation
- Phosphopeptide Enrichment
- Centrifuge Accessories
InertSep QuEChERS Kit High-purity extraction and cleanup kit for pesticide residue analysis in food and environmental samples.
Get the Right Column for Your Compound — InstantlyWhat compound are you analyzing? - GC Columns
- InertCap 1MS General purpose, Hydrocarbons, PCBs, High Volatile solvents, Phenols
- InertCap 1 General purpose, Hydrocarbons, PCBs, High Volatile solvents, Phenols
- InertCap 5MS/Sil General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 5MS/NP General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 5 General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 624MS Residual solvents of Pharmaceuticals, VOCs, Alcohols
- All GC Columns visible-xs
Get the Right Column for Your Compound — InstantlyWhat compound are you analyzing? - Instruments
LD249 Gas Leak Detector Compact, easy-to-use leak detector with thermal conductivity sensor for fast, accurate gas detection. Replaces the LD239.
FM4: Air Sampler for PFAS Low-volume air sampler for PFAS enabling comprehensive analysis of both gas and particle phases in a single sampling using stage-optimized materials.
Intelligent Pump UI-32 Series Next-generation dual-plunger HPLC pump with ultra-low pulsation and automated pressure control for flow chemistry.
OralChroma Halitosis Measuring Device High-precision breath analyzer using gas chromatography to quantify VSCs in 4 minutes — fast, reliable, and maintenance-free.
- LD249 Gas Leak Detector Latest model replacing LD239, with thermal conductivity detection for helium, hydrogen, and other gases.
GF1010 Digital Gas Flowmeter Portable, volumetric meter for accurate GC gas flow measurement without gas selection.
- Intelligent Pump UI-32 Series Next-generation dual-plunger HPLC pump with ultra-low pulsation and automated pressure control for flow chemistry.
Intelligent Micro Pump MP-32 Series Compact micro pump with ultra-low pulsation and high-pressure stability, ideal for flow chemistry and precision dosing.
Auto BPR BP-11 Auto Back Pressure Regulator for the UI-22 Series, maintaining stable pressure for consistent flow.
PCS Pump SP-32 Series Single plunger pump with real-time pressure control and low-pulsation flow—ideal for precise fluid delivery.- All HPLC Pumps visible-xs
Gastorr AG Series Reliable, CPU-controlled degassing system for low-flow applications with independent chamber design.
Gastorr BG Series High-performance degassing system with real-time vacuum display and independent chamber design.
Gastorr FG-42 Solvent degassing system optimized for fluorinated solvents with real-time vacuum display.
Gastorr PG Series High-flow degassing system for fractionating applications with real-time vacuum display.- All Degassing Units visible-xs
- Accessories
- Close Menu ×
- HPLC Accesories
- SPE Accessories
- GC Accessories
- HPLC Tubing
- Filters
- HPLC Fittings
- Solvent Bottle Caps and Other Accessories
- Gradient Mixer
- Regulator
- IDEX Accessories
- HPLC Column Hardware and Other Accessories
- Vials
- SPE Vacuum Manifolds
- SPE Gravity Manifolds
- Cleanup/Separating Bulks
- Glass Chromatography Columns
- General SPE Accessories
- Applications & Industries
- Close Menu ×
- Featured
- PFAS Solutions Products and workflows for EPA and ISO-compliant PFAS testing in water, air, and soil.
- Flow Chemistry Solutions Integrated pumps and pressure regulators for continuous, high-temperature flow chemistry reactions.
- Life Science/Bio Products Spin columns and purification tools for antibody capture, protein cleanup, and bioseparation workflows.
- Gas/Air Sampling Equipment Sampling tools for capturing VOCs, aldehydes, and trace gases in environmental and industrial settings.
- Resources
- About
- Contact Us
Search
You have no items in your shopping cart.
- HPLC Columns
- Sample Preparation
- GC Columns
- Instruments
- LD249 Gas Leak Detector Compact, easy-to-use leak detector with thermal conductivity sensor for fast, accurate gas detection. Replaces the LD239.
- FM4: Air Sampler for PFAS Low-volume air sampler for PFAS enabling comprehensive analysis of both gas and particle phases in a single sampling using stage-optimized materials.
- Intelligent Pump UI-32 Series Next-generation dual-plunger HPLC pump with ultra-low pulsation and automated pressure control for flow chemistry.
- OralChroma Halitosis Measuring Device High-precision breath analyzer using gas chromatography to quantify VSCs in 4 minutes — fast, reliable, and maintenance-free.
- Accessories
- Applications & Industries
- Resources
- About
- Contact Us
HPLC Column Equivalent List
Looking to replace an HPLC column from another brand? Use this searchable reference to find equivalent options for Waters, Agilent, Phenomenex, and many more. Whether you're validating methods or ensuring compatibility, this list helps you quickly locate the right match across popular HPLC column lines. Choose a brand to find matching GL Sciences columns.
Column Equivalents Chart
Use this table to find equivalent columns from different manufacturers. All columns listed have similar selectivity characteristics for most applications.
Agilent
Poroshell · Zorbax · Pursuit & more
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Poroshell 120 EC-C18 | InertCore Plus C18 | InertCore Plus C18 |
| Poroshell 120 EC-C8 | InertCore C8 | InertCore C8 |
| Poroshell 120 EC-CN | – | InertSustain Cyano |
| Poroshell 120 HILIC | – | Inertsil HILIC |
| Poroshell 120 PFP | – | InertSustain PFP |
| Poroshell 120 Phenyl-Hexyl | – | InertSustain Phenylhexyl |
| Poroshell 120 SB-C18 | InertCore Plus C18 | InertCore Plus C18 |
| Poroshell 120 SB-C8 | InertCore C8 | InertCore C8 |
| Poroshell 300 Extend C18 | – | InertCore Plus C18 |
| Poroshell 300 SB-C18 | – | InertSustainSwift C18 |
| Poroshell 300 SB-C8 | – | InertSustainSwift C8 |
| Poroshell HPH-C18 | – | InertCore Plus C18 |
| Poroshell HPH-C8 | InertCore C8 | InertCore C8 |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Prep C18 | Inertsil ODS-HL | Inertsil ODS-HL |
| Pursuit XRS C18 | InertSustain C18 | InertSustain C18 |
| Pursuit XRS C8 | InertSustain C8 | InertSustain C8 |
| Pursuit XRS Diphenyl | – | InertSustain Phenylhexyl |
| Pursuit XRS Ultra 2.8 C18 | InertSustainSwift C18 | InertSustainSwift C18 |
| Pursuit XRS Ultra 2.8 C8 | InertSustainSwift C8 | InertSustainSwift C8 |
| Pursuit XRS Ultra 2.8 DiPhenyl | – | InertSustain Phenylhexyl |
Waters
ACQUITY · CORTECS · XBridge · Symmetry · Spherisorb & more
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Symmetry C18 | InertSustain C18 | InertSustain C18 |
| Symmetry C8 | InertSustain C8 | InertSustain C8 |
| Symmetry Prep C18 | InertSustain C18 | InertSustain C18 |
| Symmetry Prep C8 | InertSustain C8 | InertSustain C8 |
| Symmetry Shield RP 8 | InertSustain C8 | InertSustain C8 |
| Symmetry300 C18 | Inertsil WP300 C18 | InertSustainSwift C18 |
| Symmetry300 C4 | Inertsil WP300 C4 | Inertsil WP300 C4 |
| SymmetryShield RP18 | Inertsil ODS-EP | InertSustain AQ-C18 |
| SymmetryShield RP8 | – | InertSustain C8 |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Spherisorb C1 | Inertsil TMS | Inertsil TMS |
| Spherisorb C8 | InertSustainSwift C8 | InertSustainSwift C8 |
| Spherisorb CN | InertSustain Cyano | InertSustain Cyano |
| Spherisorb NH2 | InertSustain NH2 | InertSustain NH2 |
| Spherisorb ODS1 | – | InertSustainSwift C18 |
| Spherisorb ODS2 | – | InertSustainSwift C18 |
| Spherisorb ODSB | – | InertSustainSwift C18 |
| Spherisorb Phenyl | InertSustain Phenyl | InertSustain Phenyl |
| Spherisorb SCX | Inertsil CX | Inertsil CX |
| Spherisorb W (silica) | Inertsil SIL-100A | Inertsil SIL-100A |
Phenomenex
Kinetex · Luna · Gemini · Synergi · Prodigy & more
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Kinetex Biphenyl | InertCore Biphenyl | InertCore Biphenyl |
| Kinetex C18 | InertCore Plus C18 | InertCore Plus C18 |
| Kinetex C8 | InertCore C8 | InertCore C8 |
| Kinetex EVO C18 | – | InertCore Plus C18 |
| Kinetex F5 | – | InertSustain PFP |
| Kinetex HILIC | – | Inertsil SIL-100A |
| Kinetex PAH | – | Inertsil ODS-P |
| Kinetex Phenyl-Hexyl | – | InertCore Biphenyl |
| Kinetex Polar-C18 | – | InertCore Plus C18 |
| Kinetex PS C18 | – | InertCore Plus C18 |
| Kinetex XB-C18 | – | InertCore Plus C18 |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Luna C18(2) | InertSustain C18 | InertSustain C18 |
| Luna C8(2) | InertSustain C8 | InertSustain C8 |
| Luna CN | InertSustain Cyano | InertSustain Cyano |
| Luna HILIC | Inertsil HILIC | Inertsil HILIC |
| Luna NH2 | InertSustain NH2 | InertSustain NH2 |
| Luna Omega C18 | InertSustain C18 | InertSustain C18 |
| Luna Omega Polar C18 | – | Inertsil ODS-EP |
| Luna Omega PS C18 | InertSustain C18 | InertSustain AX-C18 |
| Luna PFP(2) | InertSustain PFP | InertSustain PFP |
| Luna Phenyl-Hexyl | InertSustain Phenylhexyl | InertSustain Phenylhexyl |
| Luna SCX | Inertsil CX | Inertsil CX |
| Luna Silica(2) | Inertsil SIL-100A | Inertsil SIL-100A |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Gemini C18 | Inertsil Hybrid-C18 | Inertsil Hybrid-C18 |
| Gemini C6-Phenyl | InertSustain Phenylhexyl | InertSustain Phenylhexyl |
| Gemini-NX C18 | Inertsil Hybrid-C18 | Inertsil Hybrid-C18 |
| Synergi Fusion-RP | Inertsil ODS-EP | InertSustain AQ-C18 |
| Synergi Hydro-RP | InertSustain AQ-C18 | InertSustain AQ-C18 |
| Synergi Polar-RP | – | InertSustain Phenyl |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Aeris PEPTIDE XB-C18 | – | InertSustainSwift C18 |
| Aeris WIDEPORE XB-C18 | – | Inertsil WP300 C18 |
| Aeris WIDEPORE XB-C4 | – | Inertsil WP300 C4 |
| Aeris WIDEPORE XB-C8 | – | Inertsil WP300 C8 |
| bioZen dSEC-2 | – | Inertsil WP300 Diol |
| bioZen Peptide PS-C18 | InertSustainBio C18 | InertSustainBio C18 |
| bioZen Peptide XB-C18 | InertSustainBio C18 | InertSustainBio C18 |
| Jupiter 300 C18 | Inertsil WP300 C18 | InertSustainBio C18 |
| Jupiter 300 C4 | Inertsil WP300 C4 | Inertsil WP300 C4 |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Prodigy C8 | Inertsil C8 | InertSustain C8 |
| Prodigy ODS-2 | Inertsil ODS-2 | InertSustain C18 |
| Prodigy ODS-3 | Inertsil ODS-3 | InertSustain C18 |
| Prodigy ODS-3V | Inertsil ODS-3V | InertSustain C18 |
| Prodigy Phenyl-3 | Inertsil Ph-3 | InertSustain Phenylhexyl |
| Prodigy Silica | Inertsil SIL-100A | Inertsil SIL-100A |
| Prodigy Silica-3 | Inertsil SIL-100A | Inertsil SIL-100A |
Thermo Fisher Scientific
Hypersil · Accucore · Syncronis · BioBasic & more
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Acclaim 120 C18 | InertSustain C18 | InertSustain C18 |
| Acclaim 300 C18 | Inertsil WP300 C18 | Inertsil WP300 C18 |
| Acclaim C30 | InertSustain C30 | InertSustain C30 |
| Acclaim Phenyl-1 | Inertsil Ph | InertSustain Phenylhexyl |
| Accucore 150-C4 | – | Inertsil C4 |
| Accucore aQ | InertCore Plus C18 | InertCore Plus C18 |
| Accucore C30 | – | InertSustain C30 |
| Accucore C8 | InertCore C8 | InertCore C8 |
| Accucore HILIC | – | Inertsil SIL-100A |
| Accucore PFP | – | InertSustain PFP |
| Accucore Phenyl-Hexyl | – | InertCore Biphenyl |
| Accucore Phenyl-X | – | InertCore Biphenyl |
| Accucore RP-MS | – | InertSustain C18 |
| Accucore Urea HILIC | – | Inertsil HILIC |
| Accucore XL C8 | InertCore C8 | InertSustain C8 |
| Accucore™ 150 C18 | InertCore Plus C18 | InertCore Plus C18 |
| Accucore™ aQ C18 EP EC | InertCore Plus C18 | InertCore Plus C18 |
| Accucore™ C18 | InertCore Plus C18 | InertCore Plus C18 |
| Accucore™ Vanquish™ C18 | InertCore Plus C18 | InertCore Plus C18 |
| Accucore™ XL C18 | InertCore Plus C18 | InertCore Plus C18 |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| BioBasic 18 | Inertsil WP300 C18 | Inertsil WP300 C18 |
| BioBasic 4 | Inertsil WP300 C4 | Inertsil WP300 C4 |
| BioBasic 8 | Inertsil WP300 C8 | Inertsil WP300 C8 |
| BioBasic CN | Inertsil CN-3 | Inertsil CN-3 |
| BioBasic Phenyl | InertSustain Phenyl | InertSustain Phenyl |
| BioBasic SCX | Inertsil CX | Inertsil CX |
| BioBasic SEC1000 | Inertsil Diol | Inertsil Diol |
| BioBasic SEC120 | Inertsil Diol | Inertsil Diol |
| BioBasic SEC300 | Inertsil WP300 Diol | Inertsil WP300 Diol |
| BioBasic SEC60 | Inertsil Diol | Inertsil Diol |
| Syncronis Amino | InertSustain NH2 | InertSustain NH2 |
| Syncronis aQ | InertSustain C18-AQ | InertSustain C18-AQ |
| Syncronis C18 | InertSustain C18 | InertSustain C18 |
| Syncronis C8 | InertSustain C8 | InertSustain C8 |
| Syncronis HILIC | – | Inertsil HILIC |
| Syncronis Phenyl | Inertsil Ph | InertSustain Phenylhexyl |
| Syncronis Silica | Inertsil SIL-100A | Inertsil SIL-100A |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Betasil C1 | Inertsil TMS | Inertsil TMS |
| Betasil C18 | InertSustain C18 | InertSustain C18 |
| Betasil C8 | Inertsil C8 | Inertsil C8 |
| Betasil CN | Inertsil CN-3 | InertSustain Cyano |
| Betasil Diol 100 | Inertsil Diol | Inertsil Diol |
| Betasil Phenyl | Inertsil Ph | InertSustain Phenylhexyl |
| Betasil Phenyl/Hexyl | InertSustain Phenylhexyl | InertSustain Phenylhexyl |
| Betasil Silica 100 | Inertsil SIL-100A | Inertsil SIL-100A |
| Thermo CN | Inertsil CN-3 | InertSustain Cyano |
Sigma-Aldrich / Merck
Ascentis · SUPELCOSIL · LiChrospher · Purospher & more
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Ascentis C18 | Inertsil ODS-HL | Inertsil ODS-HL |
| Ascentis C8 | InertSustain C8 | InertSustain C8 |
| Ascentis ES Cyano | InertSustain Cyano | InertSustain Cyano |
| Ascentis Express AQ-C18 | – | InertSustainSwift C18 |
| Ascentis Express C18 | InertCore Plus C18 | InertCore Plus C18 |
| Ascentis Express C8 | InertCore C8 | InertCore C8 |
| Ascentis Express F5 | InertSustain PFP | InertSustain PFP |
| Ascentis Express Peptide ES-C18 | InertCore Plus C18 | InertCore Plus C18 |
| Ascentis HS F5 | InertSustain PFP | InertSustain PFP |
| Ascentis Phenyl | – | InertSustain Phenylhexyl |
| Ascentis RP-Amide | – | InertSustainSwift C18 |
| Ascentis Silica | Inertsil SIL-100A | Inertsil SIL-100A |
| BIOshell A160 Peptide C18 | – | InertCore Plus C18 |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| SUPELCOSIL LC-1 | Inertsil TMS | Inertsil TMS |
| SUPELCOSIL LC-18-DB | InertSustain C18 | InertSustain C18 |
| SUPELCOSIL LC-18-S | InertSustainSwift C18 | InertSustainSwift C18 |
| SUPELCOSIL LC-8 | InertSustainSwift C8 | InertSustainSwift C8 |
| SUPELCOSIL LC-8-DB | InertSustainSwift C8 | InertSustainSwift C8 |
| SUPELCOSIL LC-C18 | InertSustainSwift C18 | InertSustainSwift C18 |
| SUPELCOSIL LC-C18-T | InertSustainSwift C18 | InertSustainSwift C18 |
| SUPELCOSIL LC-CN | InertSustain Cyano | InertSustain Cyano |
| SUPELCOSIL LC-DP | – | InertSustain Phenylhexyl |
| SUPELCOSIL LC-NH2 | InertSustain NH2 | InertSustain NH2 |
| SUPELCOSIL LC-PAH | Inertsil ODS-P | Inertsil ODS-P |
| SUPELCOSIL LC-Si | Inertsil SIL-150A | Inertsil SIL-100A |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Discovery BIO Wide pore C18 | Inertsil WP300 C18 | InertSustainSwift C18 |
| Discovery BIO Wide pore C5 | – | Inertsil WP300 C4 |
| Discovery BIO Wide pore C8 | Inertsil WP300 C8 | InertSustainSwift C8 |
| Discovery C18 | InertSustainSwift C18 | InertSustainSwift C18 |
| Discovery C8 | InertSustainSwift C8 | InertSustainSwift C8 |
| Discovery Cyano | InertSustain Cyano | InertSustain Cyano |
| Discovery HS C18 | InertSustain C18 | InertSustain C18 |
| Discovery HS F5 | InertSustain PFP | InertSustain PFP |
| Discovery RP-Amide C16 | – | InertSustainSwift C18 |
| SeQuant ZIC-cHILIC | – | InertSustain Amide |
| SeQuant ZIC-HILIC | – | InertSustain Amide |
| SeQuant ZIC-pHILIC | – | InertSustain Amide |
| Titan C18 | Inertsil ODS-3 | InertSustain C18 |
YMC
YMC-Pack · YMC-Triart · Meteoric & more
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Meteoric Core C18 | InertCore Plus C18 | InertCore Plus C18 |
| Meteoric Core C18 BIO | InertCore Plus C18 | InertCore Plus C18 |
| YMC-Triart Bio C18 | InertSustainSwift C18 | InertSustainSwift C18 |
| YMC-Triart Bio C4 | Inertsil WP300 C4 | Inertsil WP300 C4 |
| YMC-Triart C18 | Inertsil Hybrid-C18 | Inertsil Hybrid-C18 |
| YMC-Triart C18 ExRS | Inertsil Hybrid-C18 | Inertsil ODS-HL |
| YMC-Triart C8 | InertSustain C8 | InertSustain C8 |
| YMC-Triart Diol-HILIC | Inertsil HILIC | Inertsil HILIC |
| YMC-Triart PFP | InertSustain PFP | InertSustain PFP |
| YMC-Triart Phenyl | InertSustain Phenylhexyl | InertSustain Phenylhexyl |
| YMC-Triart SIL | Inertsil SIL-100A | Inertsil SIL-100A |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| YMC Basic | InertSustainSwift C8 | InertSustainSwift C8 |
| YMC J'Sphere ODS H80 | Inertsil ODS-HL | Inertsil ODS-HL |
| YMC J'Sphere ODS L80 | InertSustainSwift C18 | InertSustainSwift C18 |
| YMC J'Sphere ODS M80 | InertSustain C18 | InertSustain C18 |
| YMC-SEC MAB | Inertsil WP300 Diol | Inertsil WP300 Diol |
| YMC-UltraHT Hydrosphere C18 | InertSustain AQ-C18 | InertSustain AQ-C18 |
| YMC-UltraHT Pro C18 | InertSustain C18 | InertSustain C18 |
Restek
Raptor · Roc · Pinnacle · Ultra · Force & more
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Raptor ARC-18 | InertCore Plus C18 | InertCore Plus C18 |
| Raptor C18 | InertCore Plus C18 | InertCore Plus C18 |
| Raptor FluoroPhenyl | – | InertSustain PFP |
| Raptor HILIC-Si | – | Inertsil SIL-100A |
| Roc C18 | InertSustain C18 | InertSustain C18 |
| Roc C8 | InertSustain C8 | InertSustain C8 |
| Roc Cyano | InertSustain Cyano | InertSustain Cyano |
| Roc Phenyl-Hexyl | InertSustain Phenylhexyl | InertSustain Phenylhexyl |
| Roc Silica | Inertsil SIL-100A | Inertsil SIL-100A |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Pinnacle C1 | – | Inertsil TMS |
| Pinnacle C18 | InertSustainSwift C18 | InertSustainSwift C18 |
| Pinnacle C4 | Inertsil C4 | Inertsil C4 |
| Pinnacle DB Aqueous C18 | InertSustain AQ-C18 | InertSustain AQ-C18 |
| Pinnacle DB Biphenyl | – | InertSustain Phenylhexyl |
| Pinnacle DB C18 | InertSustainSwift C18 | InertSustainSwift C18 |
| Pinnacle DB C8 | InertSustain C8 | InertSustain C8 |
| Pinnacle DB Cyano | InertSustain Cyano | InertSustain Cyano |
| Pinnacle DB PFP Propyl | InertSustain PFP | InertSustain PFP |
| Pinnacle DB Phenyl | InertSustain Phenyl | InertSustain Phenyl |
| Pinnacle II Cyano | InertSustain Cyano | InertSustain Cyano |
| Pinnacle II PAH | Inertsil ODS-P | Inertsil ODS-P |
| Pinnacle NH2 | InertSustain NH2 | InertSustain NH2 |
| Pinnacle Phenyl | InertSustain Phenyl | InertSustain Phenyl |
| Pinnacle Silica | Inertsil SIL-150A | Inertsil SIL-100A |
| Pinnacle Ultra C18 | InertSustain C18 | InertSustain C18 |
| Pinnacle Wide Pore C4 | Inertsil WP300 C4 | Inertsil WP300 C4 |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Force Biphenyl | – | InertSustain Phenylhexyl |
| Force C18 | InertSustain C18 | InertSustain C18 |
| Force FluoroPhenyl | InertSustain PFP | InertSustain PFP |
| Ultra Aqueous C18 | Inertsil ODS-P | InertSustain AQ-C18 |
| Ultra Aromax | Inertsil Ph | InertSustain Phenylhexyl |
| Ultra Biphenyl | – | InertSustain Phenylhexyl |
| Ultra C1 | Inertsil TMS | Inertsil TMS |
| Ultra C18 | Inertsil ODS-HL | Inertsil ODS-HL |
| Ultra C4 | Inertsil C4 | Inertsil C4 |
| Ultra C8 | InertSustain C8 | InertSustain C8 |
| Ultra Cyano | InertSustain Cyano | InertSustain Cyano |
| Ultra II C18 | InertSustain C18 | InertSustain C18 |
| Ultra PFP | InertSustain PFP | InertSustain PFP |
| Ultra Phenyl | InertSustain Phenyl | InertSustain Phenyl |
| Your Column | Direct Replacement | Alternative |
|---|---|---|
| Allure AK | – | InertSustain C18 |
| Allure Aqueous C18 | InertSustain AQ-C18 | InertSustain AQ-C18 |
| Allure Basix | InertSustain Cyano | InertSustain Cyano |
| Allure Biphenyl | – | InertSustain Phenylhexyl |
| Allure C18 | InertSustain C18 | InertSustain C18 |
| Allure Organic Acids | InertSustain AQ-C18 | InertSustain AQ-C18 |
| Viva C18 | Inertsil WP300 C18 | Inertsil WP300 C18 |
| Viva C4 | Inertsil WP300 C4 | Inertsil WP300 C4 |
| Viva C8 | Inertsil WP300 C8 | Inertsil WP300 C8 |
| Viva PFP Propyl | InertSustain PFP | InertSustain PFP |
Download Resource
Download HPLC Column Equivalent Chart (PDF) ↓
Full 497-column cross-reference across 7 brands
Need help selecting the right column equivalent?
Connect with a GL Sciences HPLC Column specialist to find better performing alternatives or replacements.
Contact Expert →
Browse HPLC Columns
Available in different sizes & column dimensions
Application Notes
Find the right column for your application
- Home /
- HPLC Columns /
- HPLC Column Equivalents
Categories
- GC Columns
- HPLC Columns
- C18 Columns
- Core-shell Columns
- C8 & C4 HPLC Columns
- C30 HPLC Columns
- PFP & Phenyl HPLC Columns
- Cyano HPLC Columns
- HILIC HPLC Columns
- Normal Phase HPLC Columns
- SEC HPLC Columns
- Ion Exchange HPLC Columns
- Monolithic HPLC Columns
- Reversed Phase HPLC Columns
- Bioseparation LC columns
- Application Specific Columns
- HPLC Guard Columns
- Preparative HPLC Columns
- HPLC Column Equivalents
- GC Accessories
- Sample Preparation
- Life Science/Bio Products
- Gas/Air Sampling Equipment
- Other Products
- Instruments
- HPLC Accessories
Get Chromatography Methods That Save You Time — Backed by Real Data
Sign up to receive chromatography methods and practical insights designed to save you time and support real-world workflows.
Wait...
We respect your privacy & will never share your information.
Contact Info
- Contact Us
- Torrance, CA, USA
Customer Service
My Account
Copyright © 2026 GL Sciences Inc.. All rights reserved.