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GL Sciences HPLC Columns

The most trusted HPLC columns since 1968.  Our wide range of phases offer reliable equivalents to Phenomenex HPLC columns.


High Inertness
Low Back Pressure
High Reproducibility

Product Reviews

 

“The (InertSustain) columns showed very good stability & reproducibility of the separation when utilized for a period of about six month with hundreds of injections.  The columns are stable in a wide range of pH & perfectly suitable for separations followed by MS detection. “

Dr. Serban Moldoveanu, RJ Reynolds Tobacco Co.

 

"I was using the corresponding InertSustain (column) and was pleased with the results.  The column looks to have a much longer lifetime."

David Budac, Ph.D, Principal Scientist, PsychoGenics

 

“I was very impressed by the performance of the InertSustain C18 column. Thank you again for suggesting it and sending us one to try!”

Anthony R. Horner, Ph.D,  Research Chemist, PPG

 

Discover The Advantages of GL Sciences' InertSustain HPLC Columns

GL Sciences next generation HPLC Columns, InertSustain employ a radically new type of silica, in which the surface of the silica is uniquely modified, enabling precise control of the silica properties.  

InertSustain inherits the advantages of all the current Inertsil HPLC columns (e.g., extremely low operating back pressure, superior inertness to typically any analytes, high efficiency & compatibility with a wide range of solvents), and now can be used for wide pH analysis with consistent performance from column-to-column and lot-to-lot.

InertSustain HPLC Columns Deliver:

 

Features

InertSustain employs a radically new type of silica, in which the surface of the silica is uniquely modified, enabling precise control of the silica properties and adsorption sites and silanol distribution are strictly controlled.

Unmatched Inertness & Durability

1st Stage
[Synthesis of “Evolved Surface Silica”]
As the adsorption sites and silanol distribution are strictly controlled from the synthesis procedure of the Evolved Surface Silica, InertSustain delivers unmatched inertness to virtually any type of analyte with high durability to acidic, basic mobile phase conditions.
2nd Stage
[Chemical Bonding of ODS group]
The introduction of Evolved Surface Silica and our cutting-edge chemical bonding technology make InertSustain compatible with 100 % aqueous mobile phases, while maintaining strong non-polar retentivity.
3rd Stage
[Complete End-capping]
GL Sciences’ complete end-capping technology allows InertSustain to provide high efficiency and superior peak shape even to those well-known strong adsorptive analytes.

Excellent Peak Resolution

Get clear separation with excellent pick shape for all types of analytes using InertSustain.

Basic Compound

Acidic Compound

Chelating Compound


Reliable Reproducibility

High inertness also provides consistent results through multiple runs and InertSustain's envolved surface silica production method allows for reproducibility across different particle sizes.


Wide pH Compatibility

InertSustain provides higher pH stability compare to competitors. Good end-capping enables high theoretical plates to be maintained even after extended exposure to extreme pH conditions. With InertSustain, analysis results are not affected by sample or mobile phase conditions.


Extremely Low Operating Back Pressure

InertSustain provides excellent column lifetime thanks to having low operating back pressure. Precise manufacturing of silica particles allows for uniform particle with equal distribution and dimension providing superior flow. The extreme low back pressure of InertSustain columns ensure long service life leading to less running costs.


Batch to Batch Reproducibility

InertSustain is delivered with consistent lot performance thanks to GL Sciences' state-of-the-art column manufacturing technology.

Recommended GL Sciences Equivalent Columns For Phenomenex

C18 Columns

Manufacturer Column Bonding Type USP GL Sciences Recommended Alternatives
Phenomenex Kinetex C18 C18 L1 InertCore C18
Phenomenex Luna C18 C18 L1 InertSustain C18
Phenomenex Luna C18(2) C18 L1 InertSustain C18
Phenomenex Luna Omega C18 C18 L1 InertSustain C18
Phenomenex Luna PS C18 C18 L1 InertSustain AQ-C18
Phenomenex Gemini C18 C18 L1 InertSustain C18
Phenomenex Gemini-NX C18 C18 L1 InertSustain C18
Phenomenex Aqua C18 C18 L1 InertSustain AQ-C18
Phenomenex Bondclone C18 C18 L1 InertSustainSwift C18
Phenomenex Columbus C18 C18 L1 InertSustain C18
Phenomenex HyperClone BDS C18 C18 L1 InertSustainSwift C18
Phenomenex HyperClone ODS(C18) C18 L1 InertSustainSwift C18
Phenomenex Jupiter 300 C18 C18 L1 Inertsil WP300 C18
Phenomenex Phenosphere ODS(1) C18 L1 InertSustainSwift C18
Phenomenex Phenosphere ODS(2) C18 L1 InertSustainSwift C18
Phenomenex Prodigy ODS-2 C18 L1 Inertsil ODS-2
Phenomenex Prodigy ODS-3 C18 L1 Inertsil ODS-3
Phenomenex Prodigy ODS-3V C18 L1 Inertsil ODS-3V
Phenomenex Selectosil C18 C18 L1 InertSustain C18
Phenomenex SphereClone ODS(1) C18 L1 InertSustainSwift C18
Phenomenex SphereClone ODS(2) C18 L1 InertSustain C18
Phenomenex Synergi Fusion-RP C18+polar L1 Inertsil ODS-EP
Phenomenex Synergi Hydro-RP C18+polar L1 InertSustain AQ-C18
Phenomenex Ultracarb ODS (20) C18 L1 Inertsil ODS-HL
Phenomenex Ultracarb ODS (30) C18 L1 Inertsil ODS-HL

Other HPLC Columns

Manufacturer Column Bonding Type USP GL Sciences Recommended Alternatives
Phenomenex Bondclone Sil Silica L3 Inertsil SIL-150A
Phenomenex HyperClone Silica Silica L3 Inertsil WP300 SIL
Phenomenex Luna Silica (2) Silica L3 Inertsil SIL-100A
Phenomenex Prodigy Silica Silica L3 Inertsil SIL-100A
Phenomenex SphereClone Silica Silica L3 Inertsil SIL-100A
Phenomenex Columbus C8 C8 L7 InertSustain C8
Phenomenex HyperClone BDS C8 C8 L7 InertSustainSwift C8
Phenomenex HyperClone MOS(C8) C8 L7 InertSustainSwift C8
Phenomenex Luna C8 C8 L7 InertSustain C8
Phenomenex Luna C8(2) C8 L7 InertSustain C8
Phenomenex Phenosphere C8 C8 L7 InertSustainSwift C8
Phenomenex Prodigy C8 C8 L7 Inertsil C8
Phenomenex SphereClone C8 C8 L7 InertSustainSwift C8
Phenomenex Ultracarb C8 C8 L7 Inertsil C8-3
Phenomenex Bondclone NH2 NH2 L8 InertSustain NH2
Phenomenex Luna NH2 NH2 L8 InertSustain NH2
Phenomenex Phenosphere NH2 NH2 L8 InertSustain NH2
Phenomenex SphereClone NH2 NH2 L8 InertSustain NH2
Phenomenex Luna SCX SCX L9 Inertsil CX
Phenomenex Bondclone CN CN L10 Inertsil CN-3
Phenomenex HyperClone CN CN L10 Inertsil CN-3
Phenomenex Luna CN CN L10 InertSustain Cyano
Phenomenex Phenosphere CN CN L10 Inertsil CN-3
Phenomenex Synergi Polar-RP Phenyl+polar L11 InertSustain Phenyl
Phenomenex Gemini C6-phenyl Phenyl-hexyl L11 InertSustain Phenylhexyl
Phenomenex Luna Phenyl-Hexyl Phenyl-hexyl L11 InertSustain Phenylhexyl
Phenomenex Bondclone Phenyl Phenyl L11 Inertsil Ph-3
Phenomenex Prodigy Phenyl-3 Phenyl L11 Inertsil Ph-3
Phenomenex SphereClone Phenyl Phenyl L11 InertSustain Phenyl
Phenomenex Luna HILIC Diol L20 Inertsil HILIC
Phenomenex Jupiter 300 C4 C4 L26 Inertsil WP300 C4
Phenomenex Curosil-PFP PFP L43 InertSustain PFP
Phenomenex Luna PFP(2) PFP L43 InertSustain PFP
Phenomenex Phenosphere SCX SCX   Inertsil CX
 

Documents

Applications

There are application notes for GL Sciences HPLC Columns.
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