InertSustain
HPLC Columns

Generally, silica based columns are mechanically stable and provide high efficiencies, however, they cannot be used under alkaline conditions and their residual silanol groups tend to adsorb organic bases. InertSustain employs a radically new type of silica, in which the surface of the silica is uniquely modified, enabling precise control of the silica properties.

High Inertness

Low Back Pressure

High Reproducibility

Features

InertSustain employs a radically new type of silica, in which the surface of the silica is uniquely modified, enabling precise control of the silica properties and adsorption sites and silanol distribution are strictly controlled.

Unmatched Inertness and Durability

1st Stage
[Synthesis of “Evolved Surface Silica”]

As the adsorption sites and silanol distribution are strictly controlled from the synthesis procedure of the Evolved Surface Silica, InertSustain delivers unmatched inertness to virtually any type of analyte with high durability to acidic, basic mobile phase conditions.

2nd Stage
[Chemical Bonding of ODS group]

The introduction of Evolved Surface Silica and our cutting-edge chemical bonding technology make InertSustain compatible with 100 % aqueous mobile phases, while maintaining strong non-polar retentivity.

3rd Stage
[Complete End-capping]

GL Sciences’ complete end-capping technology allows InertSustain to provide high efficiency and superior peak shape even to those well-known strong adsorptive analytes.

Excellent Peak Resolution

Get clear separation with excellent pick shape for all types of analytes using InertSustain.

Basic Compound

Acidic Compound

Chelating Compound

Reliable Reproducibility

High inertness also provides consistent results through multiple runs and InertSustain's envolved surface silica production method allows for reproducibility across different particle sizes.

Wide pH Compatibility

InertSustain provides higher pH stability compare to competitors. Good end-capping enables high theoretical plates to be maintained even after extended exposure to extreme pH conditions. With InertSustain, analysis results are not affected by sample or mobile phase conditions.

Extremely Low Operating Back Pressure

InertSustain provides excellent column lifetime thanks to having low operating back pressure. Precise manufacturing of silica particles allows for uniform particle with equal distribution and dimension providing superior flow. The extreme low back pressure of InertSustain columns ensure long service life leading to less running costs.

Batch to Batch Reproducibility

InertSustain is delivered with consistent lot performance thanks to GL Sciences' state-of-the-art column manufacturing technology.

Products

Reversed Phase Columns

Column	USP Code	Particle Size	Pore Size	Surface Area	Functional Group
InertSustain AQ-C18 HPLC Columns	L1, L96	1.9 µm, 3 µm, 3 µm HP, 5 µm	100 Å (10 nm)	350 m2/g	Octadecyl
InertSustain AX-C18	L11	3 µm, 3 µm HP, 5 µm	200 Å (20 nm)	200 m2/g	Octadecyl + Alkylamino (tertiary amine)
InertSustain C18 HPLC Columns	L1	1.9 µm, 2 µm, 3 µm, 3 µm HP, 3.5 µm, 5 µm	100 Å (10 nm)	350 m2/g	Octadecyl
InertSustain C8	L7	2 µm, 3 µm, 3 µm HP, 3.5 µm, 5 µm	100 Å (10 nm)	350 m2/g	Octyl
InertSustain Cyano	L10	3 µm, 3 µm HP, 5 µm	100 Å (10 nm)	350 m2/g	Cyanopropyl
InertSustain PFP	L43	3 µm, 3 µm HP, 5 µm	100 Å (10 nm)	350 m2/g	Pentafluorophenyl
InertSustain Phenyl	L11	2 µm, 3 µm, 3 µm HP, 5 µm	100 Å (10 nm)	350 m2/g	Phenyl
InertSustain Phenylhexyl	L11	3 µm, 3 µm HP, 5 µm	100 Å (10 nm)	350 m2/g	Phenylhexyl
InertSustainSwift C18	L1	1.9 µm, 3 µm, 3 µm HP, 5 µm	200 Å (20 nm)	200 m2/g	Octadecyl
InertSustainSwift C8	L7	1.9 µm, 3 µm, 3 µm HP, 5 µm	200 Å (20 nm)	200 m2/g	Octyl

Normal Phase Columns

Column	USP Code	Particle Size	Pore Size	Surface Area	Functional Group
InertSustain Cyano	L10	3 µm, 3 µm HP, 5 µm	100 Å (10 nm)	350 m2/g	Cyanopropyl
InertSustain NH2	L8	3 µm, 5 µm	100 Å (10 nm)	350 m2/g	Aminopropyl

HILIC Columns

Column	USP Code	Particle Size	Pore Size	Surface Area	Functional Group
InertSustain Amide	L68	1.9 µm, 3 µm, 5 µm	100 Å (10 nm)	350 m2/g	Carbamoyl
InertSustain NH2	L8	3 µm, 5 µm	100 Å (10 nm)	350 m2/g	Aminopropyl

Ion Exchange Columns

Column	USP Code	Particle Size	Pore Size	Surface Area	Functional Group
InertSustain AX-C18	L11	3 µm, 3 µm HP, 5 µm	200 Å (20 nm)	200 m2/g	Octadecyl + Alkylamino (tertiary amine)

Documents

Applications

There are application notes for InertSustain.

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InertSustain HPLC Columns