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InertSep®

GL Sciences’ InertSep SPE products contain sorbents and are created using the same advanced silicas and bonding technologies like those used to create Inertsil HPLC packings. Therefore, InertSep SPE cartridges and 96-well plates show exceptional purity, excellent reproducibility, high recoveries/low non-specific binding, low- to non-existent backgrounds from reagents used to manufacture the column housing, and rigid durability over a wide pH range.

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InertSep C18 is a silica-based sorbent modified with C18 (octadecyl) functional groups being utilized for non-polar interaction. With our high-level end-capping technology, cationic interaction with the silanol groups on the gel is virtually eliminated, which reduces adsorption of basic compounds. This sorbent is suitable for removing lipid for simultaneous analysis of ...
InertSep C18-B is a silica-based sorbent modified with C18 (octadecyl) functional groups being utilized for non-polar interaction. In addition to the interaction, secondary interaction can be expected on this mono functional, general purpose sorbent.
InertSep C18-C is a silica-based sorbent modified with C18 (octadecyl) functional groups being utilized for non-polar interaction. In addition to the general purpose non-polar interaction, secondary interaction between unbonded silanol groups on silica substrate and isolates can be expected on this trifunctional C18.
InertSep C8 is a silica-based sorbent modified with C8 (octyl) function groups that offers a weaker non-polar interaction than C18. InertSep C8 is used for isolates that are strongly retained too much on C18. With high-level end-capping, cationic interaction with the silanol groups on silica substrate is virtually eliminated and adsorption of basic compounds is reduced.
InertSep C2 is a silica-based sorbent modified with C2 (ethyl) functional groups being utilized for a weaker non-polar interaction than C8. InertSep C2 is used for isolates that are strongly retained too much on C8. As end-capping is accomplished on this sorbent, cation exchange interaction with none bonded silanol groups is virtually eliminated resulting in reduced adsorption ...
InertSep CH is a silica-based sorbent modified with cyclohexyl functional groups that gives this sorbent a similar moderate polarity with InertSep C2. InertSep CH offers a unique selectivity for the extraction of certain chemical compounds, compared with C18, C8, C2 and PH.
InertSep PH is a silica-based sorbent modified with phenyl functional groups having a similar non-polar interaction to C8. Phenyl functional group has π-π bond interaction which allows an isolate molecule bearing benzene ring, such as aromatic compounds to selectively interact with phenyl functional group on the sorbent.
InertSep C18 ENV is a C18 solid phase synthesized for water analysis. It is useful for sample treatment of anion surfactants in water.
InertSep CN is a silica-based sorbent modified with cyanopropyl functional groups. Having both non-polar and polar interactions, InertSep CN is ideal for applications in which extremely non-polar isolates would irreversibly retain on more non-polar sorbents such as C18 or C8 and very polar isolates might be retained irreversibly on the most polar sorbents such as SI or 2OH.
InertSep 2OH is a silica-based sorbent modified with diol functional groups. Being a fairly polar sorbent, InertSep 2OH is typically used for polar extractions from low-polar or non-polar solvents.
InertSep SI is a bare silica, which has strong polar interaction. It offers selective separation for similar compounds in structure using low-polar solvents. InertSep SI is regarded as the most polar sorbent available. Care should be taken with humidity and polar solvents, when using this material.
InertSep AL-A is packed with alumina (Al2O3). Available in Al2O3 acidic format.
InertSep AL-B is packed with alumina (Al2O3). Available in Al2O3 basic format.
InertSep AL-N is packed with alumina (Al2O3). Available in Al2O3 neutral format.
Florisil SPE cartridges are packed with magnesium silica, highly polar material which strongly adsorb polar compounds from none polar matrices and typically used for sample cleanup of organic extracts.
InertSep FL-PR cartridges are packed with FL-PR, which is used for sample cleanup for analysis of residual pesticides in crops. This sorbent is also good at viscous sample and large volume sample to expedite the procedure.
InertSep CBA is a silica-based sorbent modified with carboxyl ethyl functional groups. The primary interactions of this sorbent are cation exchange and secondary interactions are week-polar and non-polar. This sorbent is suitable for extraction of drugs with strongly cationic amine groups.
InertSep PRS is a silica-based sorbent modified with propyl-sulfonyl functional groups. The primary interactions of this sorbent are anion exchange and secondary interactions are slightly non-polar.
InertSep SCX is a silica-based sorbent modified with benzene sulfonyl propyl functional groups. The primary interaction is a combination of both non-polar and strong cation exchange. Because the non-polar interactions on InertSep SCX is stronger than those of InertSep PRS, it is suitable for such an extraction that the combination of non-polar and strong cation exchange ...
InertSep NH2 is a silica-based sorbent modified with an amino-propyl functional groups. Anion exchange and polar interaction are combined as a primary interactions. As secondary interactions, it has weak non-polar interactions. Similar to InertSep 2OH and InertSep SI used in normal phase mode, InertSep NH2 can be used for the separation of structural isomers.
InertSep PSA is a silica-based sorbent modified with an ethylene-diamine-N-propyl functional groups. The primary interactions of this sorbent are anion exchange and secondary interactions are week non-polar.
InertSep SAX is a silica-based sorbent modified with tri-methyl amino propyl functional groups. Primary interactions are very strong anion exchange. Secondary interactions are non-polar exchange. It is generally used for the extraction of weak anions such as carboxylic acid.
InertSep PA is a special SPE modified with polyamide functional groups. Primary interactions are anion exchange and polar exchange. Secondary interactions are non-polar exchange.
InertSep C18-C FF is an arranged version of InertSep C18-C for applications that need high flow late. This sorbent is also good at viscous biological sample and large volume sample to expedite the procedure.
InertSep SI FF is an arranged version of InertSep SI for applications that need high flow late. This sorbent is also good at viscous sample and large volume sample to expedite the procedure.
InertSep NH2 FF is an arranged version of InertSep NH2 for applications that need high flow late. This sorbent is also good at viscous sample and large volume sample to expedite the procedure.
InertSep C18 FF is an arranged version of InertSep C18 for applications that need high flow late. This sorbent is also good at viscous biological sample and large volume sample to expedite the procedure.
InertSep C18-B FF is an arranged version of InertSep C18-B for applications that need high flow late. This sorbent is also good at viscous biological sample and large volume sample to expedite the procedure.
InertSep HLB is a solid-phase extraction column that can effectively extract compounds with a wide range of physical properties from non-polar to high polar.
InertSep PLS-2 is a SDB (Styrene divinylbenzene) polymer based reversed phase mode sorbent. Compared to a silica based C18 sorbent, InertSep PLS-2 has a quite higher sorbent retentive capacity and better stability in pH range.
InertSep RP-1 is a copolymer based sorbent comprised of methacrylate and SDB, it exhibits a wide enough range of retention capability from low-polar to hydrophobic compounds. It is also suit for clean up.
InertSep RP-C18 is a SDB polymer based sorbent modified with alkyl chain.
InertSep Pharma is a copolymer based sorbent comprised of nitrogen-containing methacrylate and SDB. This sorbent was developed for simultaneous screening of drug metabolites in biological sample.
InertSep PLS-3 is a copolymer based sorbent comprised of nitrogen-containing methacrylate and SDB, it exhibits a wide enough range of retention capability from highly polar to hydrophobic compounds.
InertSep RP-2 is a SDB polymer based sorbent modified with weak anion exchange and hydrogen bonding functional groups. This sorbent is suit for concentration of low-retentive polar compounds with RP-1 and simultaneous screening under polar interactions.
InertSep MPC is a SDB polymer based sorbent modified with strong cation exchange and C18 functional groups. Because of its hydrophobic and ion-exchange properties, it is useful for pretreatment of basic compounds from hydrophobic compounds in blood and urine for simultaneous analysis of metabolites. It can also be used for separation and purification of acidic, neutral, and ...
InertSep Pharma FF is an arranged version of InertSep Pharma for applications that need high flow rate and good at viscous biological sample and large volume sample.
InertSep MA-2 is a methacrylate polymer based sorbent modified with, which includes a weak anion exchange function group. Because polymer base gel occurs little secondary interaction, SPE by genuine anion exchange interaction can be achieved with this sorbent.
InertSep WAX FF is a sorbent based on styrene divinylbenzene polymer modified by a weak anion-exchange group. Its reversed-phase, anion-exchange action and exceptional retention of acidic compounds make it suitable for purification of samples containing basic and neutral impurities. By controlling the pH, it can be used to recover acidic compounds under basic conditions.
InertSep MA-1 is a methacrylate polymer based sorbent modified with strong anion exchange functional groups. The primary advantages of this sorbent are high hydrophilicity and attainability of easy and effective elution of isolates.
InertSep K-solute is packed with diatomaceous earth and ideal even for the sample to form an emulsion during liquid-liquid extraction procedure. Dedicated rack for InertSep makes the operation simple and efficient.
InertSep ME-2 is a chelating resin sorbent, developed for SPE of trace metal ions in seawater. As this sorbent does not retain Ca and Mg ions, desalting can be achieved by passing the sample through the sorbent and wash with purified water.
InertSep MC-2 is a methacrylate polymer based sorbent modified with week cation exchange functional groups. This sorbent is suitable for SPE of strong anion compounds in ion exchange mode. Because polymer base gel occurs little secondary interaction, SPE by genuine cation exchange interaction can be achieved with this sorbent.
Kits that combine various products in the InertSep series.
InertSep mini AERO series are active samplers for the analysis of Aldehydes and Ketones in outdoor gas, car cabin and exhaust gas in compliance with: Offensive Odor Control Law, Clean Air Act, and EPA. There are four types: AERO DNPH, AERO DNPH-HR, AERO Ozone Scrubber, and AERO SC, InertSep mini AERO series.
These two layer cartridges are packed with graphite carbon for removing pigments and PSA sorbent for sample cleanup of organic extracts. This consolidation of two layers achieves high sample cleanup performance which cannot be obtained only on one layer.
InertSep Phospholipid is developed for removal of phospholipids selectively and is able to minimize ion suppression of LC/MS/MS analysis. It can remove more than 90 % of phospholipids.
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