PFAS Delay Column Options
GL Sciences offers the standard PFAS Delay Column, a PFAS II configuration, and a PFAS II C18 replacement cartridge.
| Item # | Item | Description |
| 5020-90005 | PFAS Delay Column | 30 × 3.0 mm I.D. |
| 5020-90009 | Delay Column for PFAS II (GCB + C18) | PFAS II configuration |
| 5020-90010 | PFAS II C18 Cartridge | Replacement, 10 × 2.1 mm |
How the PFAS Delay Column Works
The PFAS Delay Column is installed between the pump and autosampler/injector to help delay background PFAS from the LC system and mobile phase. This helps separate system-derived PFAS background from target analyte peaks during LC/MS analysis.
Ultra high-purity activated carbon
Delay Column for PFAS Installation Position
Delay Column for PFAS Effect
A general C18 column is commonly used as the delay column in the analysis of PFAS. When a general C18 column is used, it only shows a small delay and insufficient isolation. When GL Sciences Delay column is used as shown below, better separation is obtained.
Chromatogram Using Delay Column for PFAS
The Delay column for PFAS is packed with high purity activated carbon beads, which strongly retain the background PFAS from the LC system and mobile phase. The retained PFAS compounds are eluted with 100% acetonitrile, allowing a greater separation from the analytes on the chromatogram.
Comparison of System Pressure using Delay Column for PFAS
Delay Column for PFAS does not increase the LC system pressure. Installing the Delay Column for PFAS holds system pressure at the same level as no delay column at all — while a general ODS column used as a delay column raises it.
| Delay Column | Analytical Column | System Pressure |
| None | InertSustain C18 (2.1 × 150 mm, 3 µm-HP) | 19.8 MPa |
| Delay Column for PFAS (3.0 × 30 mm) | 19.8 MPa | |
| General ODS column (2.1 × 50 mm, 3 µm) | 23 MPa |
PFAS Application Resources
Review supporting PFAS application resources, including the testing solution guide, conference poster and more.
