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HPLC Columns
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- C18 Columns
- C8 & C4 HPLC Columns
- HILIC HPLC Columns
- PFP & Phenyl HPLC Columns
- Bioseparation LC columns
- SEC HPLC Columns
- Ion Exchange HPLC Columns
- All HPLC Columns
- InertSustain C18 First choice for ultra-high inertness and high durability, delivering superior peak shapes with low back pressure.
- Inertsil ODS-3 Most popular C18, trusted for long-established methods, offering strong retentivity and high loading capacity.
- InertSustain AQ-C18 First choice for high-polarity compounds, delivering strong retention even under 100% aqueous mobile phases.
- Inertsil ODS-3V Validated version of ODS-3, designed for GLP/GMP compliance, ensuring batch-to-batch consistency.
- InertSustainSwift C18 Ultra-inert, fast-separation C18 for high-throughput LC-MS and LC-MS/MS with superior peak symmetry.
- InertSustain AX-C18 Mixed-mode C18 with anion exchange for strong retention of highly polar acidic compounds without ion-pairing.
- All C18 Columns visible-xs
- InertSustain C8 Ultra-inert C8 column for rapid analysis of hydrophobic compounds with symmetric peaks across a wide pH range.
- Inertsil C8 Ultra-pure silica C8 column for rapid analysis of hydrophobic compounds, ideal for legacy methods.
- InertSustainSwift C8 Ultra-inert C8 column for low-polarity analytes, peptides, and oligonucleotides with optimized 200Å pore size.
- Inertsil C8-3 Strong retentivity, very inert, and low back pressure, based on the same silica and bonding as Inertsil ODS-3.
- Inertsil WP 300 Wide-pore C8 column for rapid, high-resolution separation of proteins and peptides with sharper peaks.
- Inertsil C4 Low-retentivity C4 column for rapid analysis of highly hydrophobic compounds like fat-soluble vitamins.
- All C8 & C4 Columns visible-xs
- InertSustain Amide First choice for HILIC mode, offering the strongest retention of polar compounds with superior stability in water-rich conditions.
- Inertsil HILIC Diol-bonded HILIC column for excellent peak shape and strong retention of highly polar basic compounds.
- InertSustain NH2 First choice for sugar analysis, offering superior stability, reproducibility, and compatibility with weakly acidic eluents.
- Inertsil NH2 Aminopropyl column for sugar analysis, highly retentive in normal phase with superior stability and reproducibility.
- ProteoSil HILIC Bioseparation-focused HILIC column, excelling in hydrophilic compound, peptide, glycan, and oligonucleotide analysis.
- All HILIC Columns visible-xs
- InertSustain PFP A pentafluorophenyl-modified column designed for enhanced separation of structurally similar compounds through multiple retention mechanisms, including π-π, dipole, and hydrogen bonding interactions.
- InertSustain Phenyl A directly bonded phenyl group gives the InertSustain Phenyl column unique reversed-phase selectivity, ideal for separating polar compounds and structural isomers via π-π and hydrogen bonding interactions.
- InertSustain Phenylhexyl A phenylhexyl-bonded column that offers complementary selectivity to traditional alkyl-chain columns, providing high inertness, reproducibility, and low back pressure.
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Sample Preparation
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- SPE Cartridges & Columns
- Spin Columns
- Proteomics Products
- InertSep QuEChERS kit
- Cleanup/Separating Bulks
- SPE Manifolds
- ALL Sample Preparation
- InertSep C18 Silica sorbent with high end-capping, ideal for lipid removal & pesticide residue analysis.
- InertSep C18-ENV C18 sorbent with low end-capping, optimized for water analysis & anionic surfactant removal.
- InertSep HLB Versatile SPE column for extracting non-polar to highly polar compounds, with a wide pH range (1-14).
- InertSep C8 Silica sorbent with octyl groups, offering weaker retention than C18 for highly retained compounds.
- InertSep SCX Silica-based SPE column with strong cation exchange and non-polar interactions for enhanced retention.
- InertSep SAX Monofunctional C18 sorbent with medium end-capping, allowing secondary interactions for versatile use.
- All SPE Cartridges & Columns visible-xs
- MonoSpin C18 High-permeability spin column for peptide desalting, drug extraction, and fast biological sample preparation.
- MonoSpin ProA Fast Protein A spin column for high-purity IgG antibody purification with >90% recovery.
- MonoSpin C18-CX Mixed-mode spin column with C18 and cation exchange for enhanced basic drug recovery.
- MonoSpin Phospholipid TiO₂/ZrO₂-coated spin column for efficient phospholipid removal and matrix effect reduction.
- MonoSpin SAX Strong anion exchange spin column for fast extraction of acidic drugs with high recovery.
- MonoSpin TiO TiO₂ spin column for phospholipid removal and organophosphorus pesticide purification.
- All Spin Columns visible-xs
- Exosome Purification
- Desalting
- Digestion
- Fractionation
- Phosphopeptide Enrichment
- Centrifuge Accessories
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InertSep QuEChERS Kit High-purity extraction and cleanup kit for pesticide residue analysis in food and environmental samples.
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GC Columns
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- InertCap Series
- TC Series
- GC Accesories
- All GC Columns
- InertCap 1MS General purpose, Hydrocarbons, PCBs, High Volatile solvents, Phenols
- InertCap 1 General purpose, Hydrocarbons, PCBs, High Volatile solvents, Phenols
- InertCap 5MS/Sil General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 5MS/NP General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 5 General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 624MS Residual solvents of Pharmaceuticals, VOCs, Alcohols
- All GC Columns visible-xs
Get the Right Column for Your Compound — InstantlyWhat compound are you analyzing?QUICK LINKS- Application Search
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Instruments
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LD249 Gas Leak Detector Compact, easy-to-use leak detector with thermal conductivity sensor for fast, accurate gas detection. Replaces the LD239. -
FM4: Air Sampler for PFAS Low-volume air sampler for PFAS enabling comprehensive analysis of both gas and particle phases in a single sampling using stage-optimized materials. -
Intelligent Pump UI-22 Series Low-pulsation linear motor pump with precise flow control and bubble-free operation. -
OralChroma Halitosis Measuring Device High-precision breath analyzer using gas chromatography to quantify VSCs in 4 minutes — fast, reliable, and maintenance-free.
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LD249 Gas Leak Detector Latest model replacing LD239, with thermal conductivity detection for helium, hydrogen, and other gases.
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GF1010 Digital Gas Flowmeter Portable, volumetric meter for accurate GC gas flow measurement without gas selection.
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Intelligent Pump UI-22 Series Low-pulsation linear motor pump with precise flow control and bubble-free operation.
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Dual Pump KP-21 Series High-precision, medium to high-pressure pump with RS-232C control and customizable seals. -
Auto BPR BP-11 Auto Back Pressure Regulator for the UI-22 Series, maintaining stable pressure for consistent flow. -
PCS Pump SP-22 Series Single plunger pump with a pressure sensor, pulse control, and real-time pressure display for precise monitoring. -
Dual Pump KP-22 Series High-precision, low-pulsation pump with pulse control, real-time pressure display, and RS-232C control. -
PCS Pump SP-21 Series Cost-effective single plunger pump with pulse control, ideal for basic solvent dispensing. - All HPLC Pumps visible-xs
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Gastorr AG Series Reliable, CPU-controlled degassing system for low-flow applications with independent chamber design. -
Gastorr BG Series High-performance degassing system with real-time vacuum display and independent chamber design. -
Gastorr FG-42 Solvent degassing system optimized for fluorinated solvents with real-time vacuum display. -
Gastorr PG Series High-flow degassing system for fractionating applications with real-time vacuum display. - All Degassing Units visible-xs
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Accessories
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- HPLC Accesories
- SPE Accessories
- GC Accessories
- HPLC Tubing
- Filters
- HPLC Fittings
- Solvent Bottle Caps and Other Accessories
- Micro Splitter Valve
- Peak Shut-off Valve
- Gradient Mixer
- Regulator
- IDEX Accessories
- HPLC Column Hardware and Other Accessories
- SPE Vacuum Manifolds
- SPE Gravity Manifolds
- Cleanup/Separating Bulks
- Glass Chromatography Columns
- General SPE Accessories
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Applications & Industries
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- Featured
- PFAS Solutions Products and workflows for EPA and ISO-compliant PFAS testing in water, air, and soil.
- Flow Chemistry Solutions Integrated pumps and pressure regulators for continuous, high-temperature flow chemistry reactions.
- Life Science/Bio Products Spin columns and purification tools for antibody capture, protein cleanup, and bioseparation workflows.
- Gas/Air Sampling Equipment Sampling tools for capturing VOCs, aldehydes, and trace gases in environmental and industrial settings.
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Resources
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- HPLC Columns
- Sample Preparation
- GC Columns
-
Instruments
-
LD249 Gas Leak Detector Compact, easy-to-use leak detector with thermal conductivity sensor for fast, accurate gas detection. Replaces the LD239.
-
FM4: Air Sampler for PFAS Low-volume air sampler for PFAS enabling comprehensive analysis of both gas and particle phases in a single sampling using stage-optimized materials.
-
Intelligent Pump UI-22 Series Low-pulsation linear motor pump with precise flow control and bubble-free operation.
-
OralChroma Halitosis Measuring Device High-precision breath analyzer using gas chromatography to quantify VSCs in 4 minutes — fast, reliable, and maintenance-free.
-
- Accessories
- Applications & Industries
- Resources
- About
- Contact Us
C8 & C4 HPLC Columns
GL Sciences C8 and C4 columns are engineered to deliver clean peak shape, high inertness, and reproducible results — even for hydrophobic analytes and large biomolecules. Built with ultra-pure silica and advanced end-capping technology, InertSustain and ProteoSil phases reduce secondary interactions and ensure consistent performance across peptide, protein, and fat-soluble vitamin workflows. Available in 100–300 Å pore sizes, ideal for both small-molecule and wide-pore applications.
Compare
Product DetailsName⬍
Price⬍
L7
3 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$920.00 / 1 pc.
L7
5 µm
150 Å (15 nm)
320 m2/g
10.5%
Yes
$879.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$649.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$827.00 / 1 pc.
L7
10 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$827.00 / 1 pc.
L7
3.5 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$700.00 / 1 pc.
L7
3.5 µm
100 Å (10 nm)
350 m2/g
8.0%
Yes
$770.00 / 1 pc.
L7
3.5 µm
100 Å (10 nm)
450 m2/g
5.0%
Yes
$670.00 / 1 pc.
L7
1.9 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,454.00 / 1 pc.
L7
3 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,360.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$712.00 / 1 pc.
L7
5 µm
150 Å (15 nm)
320 m2/g
10.5%
Yes
$795.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
5.0%
Yes
$712.00 / 1 pc.
L7
3 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$805.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$649.00 / 1 pc.
L7
10 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$827.00 / 1 pc.
L7
1.9 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$869.00 / 1 pc.
L7
10 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$2,980.00 / 1 pc.
L7
10 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$8,290.00 / 1 pc.
L7
5 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$920.00 / 1 pc.
L7
3 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$805.00 / 1 pc.
L7
3 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,528.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
350 m2/g
8.0%
Yes
$712.00 / 1 pc.
L7
5 µm
150 Å (15 nm)
320 m2/g
10.5%
Yes
$1,308.00 / 1 pc.
L7
5 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,172.00 / 1 pc.
L7
3 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,287.00 / 1 pc.
L7
5 µm
300 Å (30 nm)
150 m2/g
4.0%
Yes
$889.00 / 1 pc.
L7
3 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$805.00 / 1 pc.
L7
3 µm HP
200 Å (20 nm)
200 m2/g
6.0%
Yes
$869.00 / 1 pc.
L7
3 µm
100 Å (10 nm)
450 m2/g
5.0%
Yes
$805.00 / 1 pc.
L7
3 µm
100 Å (10 nm)
450 m2/g
5.0%
Yes
$805.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
350 m2/g
8.0%
Yes
$597.00 / 1 pc.
L7
3 µm HP
200 Å (20 nm)
200 m2/g
6.0%
Yes
$869.00 / 1 pc.
L7
3 µm HP
200 Å (20 nm)
200 m2/g
6.0%
Yes
$869.00 / 1 pc.
L7
1.9 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$942.00 / 1 pc.
L7
3 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,329.00 / 1 pc.
L7
10 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$827.00 / 1 pc.
L7
1.9 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,402.00 / 1 pc.
L7
4 µm
100 Å (10 nm)
350 m2/g
8.0%
Yes
$754.00 / 1 pc.
L7
10 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$2,760.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
5.0%
Yes
$712.00 / 1 pc.
L7
3 µm
100 Å (10 nm)
450 m2/g
5.0%
Yes
$805.00 / 1 pc.
L7
3 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,287.00 / 1 pc.
L7
7 µm
150 Å (15 nm)
320 m2/g
10.5%
Yes
$723.00 / 1 pc.
L7
5 µm
150 Å (15 nm)
320 m2/g
10.5%
Yes
$723.00 / 1 pc.
L7
7 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$712.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$712.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
350 m2/g
8.0%
Yes
$8,200.00 / 1 pc.
L7
5 µm
100 Å (10 nm)
450 m2/g
9.0%
Yes
$712.00 / 1 pc.
L7
3 µm
200 Å (20 nm)
200 m2/g
6.0%
Yes
$1,360.00 / 1 pc.