MonoTip-TiO Phosphopeptide Enrichment Pipette Tips
MonoTip TiO pipette-based columns contain GL Sciences’ silica monolith completely coated with nanoparticles of titanium dioxide.
MonoTip TiO was GL Sciences’ first TiO2 based product for low-pressure phophopeptide enrichment, and offers the convenience of rapid enrichment and are widely used today; however, Phos- TiO centrifuge-spin columns contain an advanced form of TiO2 which provides superior selectivity and capacity and allows many individual samples to be processed simultaneously. (For new customers, we recommend evaluating Phos-TiO products as a first choice.)
MonoTip C18 pipette tips (compare to Waters' ZipTip) are available for desalting and micro-SPE / Sample Enrichment of non-phosphorylated peptides and proteins.
MonoTip are easy to use - samples are easily loaded, washed, and eluting using a pipette (single or multiple port). MonoTip TiO pipette tips are used for sample volumes of 50 - 200 μL, with approximately 5ug of phosphopeptide bound per tip. Owing to the open prorosity of the monolith contained in these tips, samples can be eluted with small volumes, thereby substantially concentrating phosphopeptides