The original 2-Series Inertsil phases, including ODS-2, C8, Ph, C4, and SIL-150A, created the high purity silica revolution in the late 1980s. These phases utilize a 99.999% pure silica get which is extremely durable and free from dents and cracks which can cause premature column failure. GL Sciences has compiled a vast collection of chromatographic applications data on ODS-2 and their other phases which can assist you in method development. These can be accessed here
By choosing Inertsil 2-Series columns, you can be assured that you are using one of the most trusted, popular, and enduring HPLC columns in the history of HPLC. The original Inertsil 2-Series of columns remain some of the most useful and popular on the market today.
However, GL Sciences' Inertsil 3-Series phases were a major advancement on the original 2-Series, and generally provide superior chromatography and alternative selectivity to the 2-Series. We recommend starting out with Inertsil SIL-100A for new methods where an unbonded silica column is most suited for the separation.