InertCore Plus C18 HPLC Column, 2.6 µm, 100 x 3.0 mm (analytical)

High Performance Core-Shell Column For UHPLC/HPLC

The molecules of the target analytes pass through the fine pores in the particles in the packing material. Core-shell particles are formed around a solid non-porous core, resulting in less diffusion inside the fine pore structure. This differs from the more traditional fully porous particle. When using a core-shell column, the distribution of molecules in the peak is narrower when the target compound is eluted from the column, resulting in a greater number of theoretical plates.

The InertCore Plus C18 columns are subjected to rigorous internal quality control from bare silica manufacturing to inspection, resulting in superior reproducibility due to shell layer homogeneity.

InertCore Plus C18

Core-shell columns from other suppliers 

Compared to other core-shell brand columns, InertCore Plus C18 delivery extremely stable batch-to-batch performance.

InertCore Plus C18

Competitor

The InertCore Plus C18 columns are subjected to rigorous internal quality control from bare silica manufacturing to inspection, resulting in superior reproducibility due to shell layer homogeneity.

InertCore Plus C18 has high durability demonstrating that the performance for retention time, theoretical plate and symmetry factor is maintained even after 2000 continuous injections.

2. Benzoic acid

3. Acetophenone

Retention time

Theoretical plates

Symmetry factor

Performance is maintained even after 2000 injections.

The results of analyses performed with the InertCore Plus C18 on two different HPLC systems, under the same conditions are shown. Peak shapes are excellent in both cases and equivalent chromatograms were obtained. 

Pressure: 22.0 MPa (including all plumbing, etc.)
Degree of separation between peak 2 and peak 3: 3.65

Pressure: 19.0 MPa (including all plumbing, etc.)
Degree of separation between peak 2 and peak 3: 3.29

＊To eliminate the effect of system volume, plumbing size, etc. A general purpose HPLC system is optimized.