HPLC Columns
- InertSustain C18 First choice for ultra-high inertness and high durability, delivering superior peak shapes with low back pressure.
- Inertsil ODS-3 Most popular C18, trusted for long-established methods, offering strong retentivity and high loading capacity.
- InertSustain AQ-C18 First choice for high-polarity compounds, delivering strong retention even under 100% aqueous mobile phases.
- Inertsil ODS-3V Validated version of ODS-3, designed for GLP/GMP compliance, ensuring batch-to-batch consistency.
- InertSustainSwift C18 Ultra-inert, fast-separation C18 for high-throughput LC-MS and LC-MS/MS with superior peak symmetry.
- InertSustain AX-C18 Mixed-mode C18 with anion exchange for strong retention of highly polar acidic compounds without ion-pairing.
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- InertCore Biphenyl Core-shell biphenyl for UHPLC/HPLC with superior π-π selectivity and strong retention of aromatic compounds.
- InertCore C8 Core-shell C8 for UHPLC/HPLC with moderate hydrophobicity, enabling fast, efficient, reproducible separations.
- InertCore Plus C18 Core-shell C18 for UHPLC/HPLC with superior reproducibility, durability, and sharp peaks.
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- InertSustain C8 Ultra-inert C8 column for rapid analysis of hydrophobic compounds with symmetric peaks across a wide pH range.
- Inertsil C8 Ultra-pure silica C8 column for rapid analysis of hydrophobic compounds, ideal for legacy methods.
- InertSustainSwift C8 Ultra-inert C8 column for low-polarity analytes, peptides, and oligonucleotides with optimized 200Å pore size.
- Inertsil C8-3 Strong retentivity, very inert, and low back pressure, based on the same silica and bonding as Inertsil ODS-3.
- Inertsil WP 300 Wide-pore C8 column for rapid, high-resolution separation of proteins and peptides with sharper peaks.
- Inertsil C4 Low-retentivity C4 column for rapid analysis of highly hydrophobic compounds like fat-soluble vitamins.
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- InertSustain Amide First choice for HILIC mode, offering the strongest retention of polar compounds with superior stability in water-rich conditions.
- Inertsil HILIC Diol-bonded HILIC column for excellent peak shape and strong retention of highly polar basic compounds.
- InertSustain NH2 First choice for sugar analysis, offering superior stability, reproducibility, and compatibility with weakly acidic eluents.
- Inertsil NH2 Aminopropyl column for sugar analysis, highly retentive in normal phase with superior stability and reproducibility.
- ProteoSil HILIC Bioseparation-focused HILIC column, excelling in hydrophilic compound, peptide, glycan, and oligonucleotide analysis.
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- InertSustain PFP A pentafluorophenyl-modified column designed for enhanced separation of structurally similar compounds through multiple retention mechanisms, including π-π, dipole, and hydrogen bonding interactions.
- InertSustain Phenyl A directly bonded phenyl group gives the InertSustain Phenyl column unique reversed-phase selectivity, ideal for separating polar compounds and structural isomers via π-π and hydrogen bonding interactions.
- InertSustain Phenylhexyl A phenylhexyl-bonded column that offers complementary selectivity to traditional alkyl-chain columns, providing high inertness, reproducibility, and low back pressure.
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- InertSep C18 Silica sorbent with high end-capping, ideal for lipid removal & pesticide residue analysis.
- InertSep C18-ENV C18 sorbent with low end-capping, optimized for water analysis & anionic surfactant removal.
- InertSep HLB Versatile SPE column for extracting non-polar to highly polar compounds, with a wide pH range (1-14).
- InertSep C8 Silica sorbent with octyl groups, offering weaker retention than C18 for highly retained compounds.
- InertSep SCX Silica-based SPE column with strong cation exchange and non-polar interactions for enhanced retention.
- InertSep SAX Monofunctional C18 sorbent with medium end-capping, allowing secondary interactions for versatile use.
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- MonoSpin C18 High-permeability spin column for peptide desalting, drug extraction, and fast biological sample preparation.
- MonoSpin ProA Fast Protein A spin column for high-purity IgG antibody purification with >90% recovery.
- MonoSpin C18-CX Mixed-mode spin column with C18 and cation exchange for enhanced basic drug recovery.
- MonoSpin Phospholipid TiO₂/ZrO₂-coated spin column for efficient phospholipid removal and matrix effect reduction.
- MonoSpin SAX Strong anion exchange spin column for fast extraction of acidic drugs with high recovery.
- MonoSpin TiO TiO₂ spin column for phospholipid removal and organophosphorus pesticide purification.
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- InertSep QuEChERS Kit High-purity extraction and cleanup kit for pesticide residue analysis in food and environmental samples.
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- InertCap 1MS General purpose, Hydrocarbons, PCBs, High Volatile solvents, Phenols
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- InertCap 5MS/NP General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 5 General purpose, Halogenated compounds, Phenols, Pesticides, FAME
- InertCap 624MS Residual solvents of Pharmaceuticals, VOCs, Alcohols
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- Intelligent Pump UI-32 Series Next-generation dual-plunger HPLC pump with ultra-low pulsation and automated pressure control for flow chemistry.
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GC Column Equivalent Chart

Looking to compare GC columns across leading brands? Use this chart below to find equivalent options for columns from Agilent, Restek, Phenomenex, and more. Search by USP code, phase chemistry, or brand label to identify compatible replacements — including GL Sciences’ InertCap series.

Looking for GC column alternatives by brand? Browse our GC Column Equivalents List.

GL Sciences	USP Code	Phase	Agilent	Restek	Trajan	Phenomenex	Thermo Fisher Scientific	Merck/Supelco	Kanto Chemical	Shinwa	Frontier Lab	Quadrex	VICI Valco	MEGA	Macherey-Nagel	Hichrom Alltech	PerkinElmer	Agela Technologies	Abel
InertCap 1MS	G1, G2, G38	100% Dimethylpolysiloxane	DB-1ms UI, HP-1ms UI, VF-1ms, CP-Sil 5 CB Low Bleed/MS	Rxi-1ms	BPX1	ZB-1 Plus	TR-1MS	Equity-1				007-1			Optima-1ms	AT-1ms	Elite-1, PE-1	DA-1MS	AB-1MS
InertCap 1	G1, G2, G38	100% Dimethylpolysiloxane	DB-1, HP-1, ULTRA-1, CP-Sil 5 CB	Rtx-1	BP1	ZB-1	TR-1	SPB-1	ENV-1	HR-1	UA⁺-1(S) , UA⁺-1	007-1	VB-1	MEGA-1	Optima-1	AT-1, EC-1	Elite-1, PE-1	DA-1	AB-1
InertCap 5MS/Sil	G27, G36	5% Diphenyl (equiv.) - Dimethylpolysilphenylene siloxane	DB-5ms, DB-5ms UI, VF-5ms	Rxi-5Sil MS Rtx-5Sil MS	BP5ms	ZB-5ms	TR-5MS	SLB-5ms	ENV-5MS			007-5MS			Optima-5ms	AT-5ms	Elite-5ms
InertCap 5MS/NP	G27, G36	5 % Diphenyl - 95 % Dimethylpolysiloxane	HP-5ms, HP-5ms UI, CP Sil 8 CB Low Bleed/MS	Rxi-5ms Rtx-5ms	BPX5	ZB-5ms	TR-5	Equity-5	ENV-5MS			007-5				AT-5ms	Elite-5ms	DA-5MS	AB-5MS
InertCap 5	G27, G36	5 % Diphenyl - 95 % Dimethylpolysiloxane	DB-5, HP-5, ULTRA-2, CP Sil 8 CB	Rtx-5	BP5	ZB-5	TR-5	SPB-5		HR-52	UA⁺-5	007-5	VB-5	MEGA-5	Optima-5	AT-5	Elite-5	DA-5	AB-5
InertCap 624MS	G43	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	DB-624 UI, VF-624ms, CP-Select 624 CB	Rtx-624Sil MS	BP624	ZB-624 Plus			ENV-624		UA-624	007-624	VB-624	MEGA-624	Optima-624 LB	AT-624	Elite-624, Elite-Volatiles, PE-Volatiles	DA-624	AB-624
InertCap 624	G43	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	DB-624, VF-624ms, CP-Select 624 CB	Rtx-624	BP624	ZB-624			ENV-624		UA-624	007-624	VB-624	MEGA-624	Optima-624	AT-624	Elite-624, Elite-Volatiles, PE-Volatiles	DA-624	AB-624
InertCap 1301	G43	6% Cyanopropylphenyl - 94% Dimethylpolysiloxane	HP-1301, VF-1301ms, CP-1301	Rtx-1301				SPB-1301				007-1301			Optima-1301	AT-1301	Elite-1301	DA-1301	AB-1301
InertCap 35MS	G42	35% Diphenyl(equiv.) - 65% Dimethylpolysiloxane	DB-35ms, DB-35ms UI, VF-35ms	Rtx-35Sil MS	BPX35	ZB-35	TR-35MS	SPB-35	ENV-35MS			007-11			OPTIMA 35 MS	AT-35	Elite-35, Elite-35ms	DA-35MS	AB-35
InertCap 35	G42	35% Diphenyl - 65% Dimethylpolysiloxane	HP-35, DB-35, VF-35ms	Rtx-35	BPX35	ZB-35	TR-35MS	SPB-35	ENV-35MS			007-11				AT-35	Elite-35, Elite-35ms	DA-35MS	AB-35
InertCap 1701MS	G46	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	DB-1701, VF-1701ms, CP-Sil 19 CB	Rtx-1701	BP10 (1701)	ZB-1701	TR-1701	SPB-1701	ENV-1701	HR-1701	UA⁺-1701	007-1701	VB-1701	MEGA-1701	Optima-1701	AT-1701	Elite-1701, PE-1701	DA-1701	AB-1701
InertCap 1701	G46	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	DB-1701, VF-1701ms, CP-Sil 19 CB	Rtx-1701	BP10 (1701)	ZB-1701	TR-1701	SPB-1701	ENV-1701	HR-1701	UA⁺-1701	007-1701	VB-1701	MEGA-1701	Optima-1701	AT-1701	Elite-1701, PE-1701	DA-1701	AB-1701
InertCap 17MS/Sil	G3	50 % Diphenyl(equiv.) - 50 % Dimethylsilphenylene Siloxane	HP-17, DB-17ms, VF-17ms, CP-Sil 24 CB Low Bleed/MS	Rxi-17	BPX50	ZB-50	TR-50MS		ENV-17MS			Elite-17ms				AT-50	Elite-17ms
InertCap 17MS	G3	50% Diphenyl - 50% Dimethylpolysiloxane	HP-17, DB-17ms, VF-17ms, CP-Sil 24 CB Low Bleed/MS	Rxi-17	BPX50	ZB-50	TR-50MS		ENV-17MS			Elite-17ms			Optima-17ms	AT-50	Elite-17ms
InertCap 17	G3	50% Diphenyl - 50% Dimethylpolysiloxane	DB-17, HP-50, CP-Sil 24 CB	Rtx-50		ZB-50		SPB-50		HR-17	UA⁺-17	007-17	VB-50	MEGA-17	Optima-17	AT-50ms	Elite-17, PE-17	DA-50+MS	AB-50+
InertCap 210	G7, G19	50 % Trifluoropropyl - 50 % Methylpolysiloxane	DB-210, DB-200, VF-200ms	Rtx-200								007-210			Optima-210	AT-210
InertCap 225	G7, G19	50 % Cyanopropylmethyl - 50 % Phenylmethylpolysiloxane	DB-225, CP Sil 43 CB	Rtx-225	BP225							007-225		MEGA-225	Optima-225	AT-225	Elite-225, PE-225
InertCap Pure-WAX	G14, G15, G16, G20, G39, G47	Polyethylene Glycol(PEG)	HP-INNOWAX, CP Wax 52 CB	Stabilwax	BP20 (WAX)	ZB-WAXplus	TR-WAX	Supelcowax 10	ENV-WAX	HR-20M	UA-CW	007-CW	VB-Wax	MEGA-WAX	Optima Wax Plus	AT-Wax	Elite-WAX, PE-CW	DA-INOWAX	AB-INOWAX
InertCap WAX	G14, G15, G16, G20, G39, G47	Polyethylene Glycol(PEG)	DB-WAX, CP Wax 52 CB	Rtx-Wax	BP20 (WAX)	ZB-Wax	TR-WAX	Supelcowax 10	ENV-WAX	HR-20M	UA-CW	007-CW	VB-Wax	MEGA-WAX	Optima Wax	AT-Wax	Elite-WAX, PE-CW	DA-INOWAX	AB-INOWAX
InertCap WAX-HT	G14, G15, G16, G20, G39, G47	Polyethylene Glycol(PEG)	DB-WAXetr, VF-WAXms, CP Wax 52 CB		Solgel WAX	ZB-Wax	TR-WAX	Supelcowax 10	ENV-WAX	HR-20M	UA-CW	007-CW	VB-Wax	MEGA-WAX	Optima Wax	AT-Wax	Elite-WAX, PE-CW	DA-INOWAX	AB-INOWAX
InertCap FFAP	G35	Nitroterephthalic acid modified Polyethylene Glycol	DB-FFAP, HP-FFAP, CP WAX 58 CB	Stabilwax-DA	BP21 (FFAP)	ZB-FFAP					UA-FFAP	007-FFAP			Optima FFAP Permabond FFAP	AT-AQUAWAX-DA, AT-1000, EC-1000	Elite-FFAP, PE-FFAP	DA-FFAP	AB-FFAP
InertCap for Amines	-	Unique	CP-Volamine	Rtx-Volatile Amines

Agilent equivalent GC columns

Agilent	Phase	USP Code	InertCap
DB-1ms UI, HP-1ms UI, VF-1ms, CP-Sil 5 CB Low Bleed/MS	100% Dimethylpolysiloxane	G1, G2, G38	InertCap 1MS
DB-1, HP-1, ULTRA-1, CP-Sil 5 CB	100% Dimethylpolysiloxane	G1, G2, G38	InertCap 1
DB-5ms, DB-5ms UI, VF-5ms	5% Diphenyl (equiv.) - Dimethylpolysilphenylene siloxane	G27, G36	InertCap 5MS/Sil
HP-5ms, HP-5ms UI, CP Sil 8 CB Low Bleed/MS	5 % Diphenyl - 95 % Dimethylpolysiloxane	G27, G36	InertCap 5MS/NP
DB-5, HP-5, ULTRA-2, CP Sil 8 CB	5 % Diphenyl - 95 % Dimethylpolysiloxane	G27, G36	InertCap 5
DB-624 UI, VF-624ms, CP-Select 624 CB	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	G43	InertCap 624MS
DB-624, VF-624ms, CP-Select 624 CB	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	G43	InertCap 624
HP-1301, VF-1301ms, CP-1301	6% Cyanopropylphenyl - 94% Dimethylpolysiloxane	G43	InertCap 1301
DB-35ms, DB-35ms UI, VF-35ms	35% Diphenyl(equiv.) - 65% Dimethylpolysiloxane	G42	InertCap 35MS
HP-35, DB-35, VF-35ms	35% Diphenyl - 65% Dimethylpolysiloxane	G42	InertCap 35
DB-1701, VF-1701ms, CP-Sil 19 CB	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	G46	InertCap 1701MS
DB-1701, VF-1701ms, CP-Sil 19 CB	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	G46	InertCap 1701
HP-17, DB-17ms, VF-17ms, CP-Sil 24 CB Low Bleed/MS	50 % Diphenyl(equiv.) - 50 % Dimethylsilphenylene Siloxane	G3	InertCap 17MS/Sil
HP-17, DB-17ms, VF-17ms, CP-Sil 24 CB Low Bleed/MS	50% Diphenyl - 50% Dimethylpolysiloxane	G3	InertCap 17MS
DB-17, HP-50, CP-Sil 24 CB	50% Diphenyl - 50% Dimethylpolysiloxane	G3	InertCap 17
DB-210, DB-200, VF-200ms	50 % Trifluoropropyl - 50 % Dimethylpolysiloxane	G6	InertCap 210
DB-225, CP Sil 43 CB	50 % Cyanopropylmethyl - 50 % Phenylmethylpolysiloxane	G7, G19	InertCap 225
HP-INNOWAX, CP Wax 52 CB	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap Pure-WAX
DB-WAX, CP Wax 52 CB	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap WAX
DB-WAXetr, VF-WAXms, CP Wax 52 CB	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap WAX-HT
DB-FFAP, HP-FFAP, CP WAX 58 CB	Nitroterephthalic acid modified Polyethylene Glycol	G35	InertCap FFAP
CP-Volamine	Unique	-	InertCap for Amines

Restek equivalent GC columns

Restek	Phase	USP Code	InertCap
Rxi-1ms	100% Dimethylpolysiloxane	G1, G2, G38	InertCap 1MS
Rtx-1	100% Dimethylpolysiloxane	G1, G2, G38	InertCap 1
Rxi-5Sil MS, Rtx-5Sil MS	5% Diphenyl (equiv.) - Dimethylpolysilphenylene siloxane	G27, G36	InertCap 5MS/Sil
Rxi-5ms, Rtx-5ms	5 % Diphenyl - 95 % Dimethylpolysiloxane	G27, G36	InertCap 5MS/NP
Rtx-5	5 % Diphenyl - 95 % Dimethylpolysiloxane	G27, G36	InertCap 5
Rtx-624Sil MS	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	G43	InertCap 624MS
Rtx-624	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	G43	InertCap 624
Rtx-1301	6% Cyanopropylphenyl - 94% Dimethylpolysiloxane	G43	InertCap 1301
Rtx-35Sil MS	35% Diphenyl(equiv.) - 65% Dimethylpolysiloxane	G42	InertCap 35MS
Rtx-35	35% Diphenyl - 65% Dimethylpolysiloxane	G42	InertCap 35
Rtx-1701	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	G46	InertCap 1701MS
Rtx-1701	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	G46	InertCap 1701
Rxi-17	50 % Diphenyl(equiv.) - 50 % Dimethylsilphenylene Siloxane	G3	InertCap 17MS/Sil
Rxi-17	50% Diphenyl - 50% Dimethylpolysiloxane	G3	InertCap 17MS
Rtx-50	50% Diphenyl - 50% Dimethylpolysiloxane	G3	InertCap 17
Rtx-200	50 % Trifluoropropyl - 50 % Dimethylpolysiloxane	G6	InertCap 210
Rtx-225	50 % Cyanopropylmethyl - 50 % Phenylmethylpolysiloxane	G7, G19	InertCap 225
Stabilwax	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap Pure-WAX
Rtx-Wax	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap WAX
Stabilwax-DA	Nitroterephthalic acid modified Polyethylene Glycol	G35	InertCap FFAP
Rtx-Volatile Amines	Unique	-	InertCap for Amines

Phenomenex equivalent GC columns

Phenomenex	Phase	USP Code	InertCap
ZB-1 Plus	100% Dimethylpolysiloxane	G1, G2, G38	InertCap 1MS
ZB-1	100% Dimethylpolysiloxane	G1, G2, G38	InertCap 1
ZB-5ms	5% Diphenyl (equiv.) - Dimethylpolysilphenylene siloxane	G27, G36	InertCap 5MS/Sil
ZB-5ms	5 % Diphenyl - 95 % Dimethylpolysiloxane	G27, G36	InertCap 5MS/NP
ZB-5	5 % Diphenyl - 95 % Dimethylpolysiloxane	G27, G36	InertCap 5
ZB-624 Plus	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	G43	InertCap 624MS
ZB-624	6 % Cyanopropylphenyl - 94 % Dimethylpolysiloxane	G43	InertCap 624
ZB-35	35% Diphenyl(equiv.) - 65% Dimethylpolysiloxane	G42	InertCap 35MS
ZB-35	35% Diphenyl - 65% Dimethylpolysiloxane	G42	InertCap 35
ZB-1701	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	G46	InertCap 1701MS
ZB-1701	14% Cyanopropylphenyl - 86% Dimethylpolysiloxane	G46	InertCap 1701
ZB-50	50 % Diphenyl(equiv.) - 50 % Dimethylsilphenylene Siloxane	G3	InertCap 17MS/Sil
ZB-50	50% Diphenyl - 50% Dimethylpolysiloxane	G3	InertCap 17MS
ZB-50	50% Diphenyl - 50% Dimethylpolysiloxane	G3	InertCap 17
ZB-WAXplus	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap Pure-WAX
ZB-Wax	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap WAX
ZB-Wax	Polyethylene Glycol(PEG)	G14, G15, G16, G20, G39, G47	InertCap WAX-HT
ZB-FFAP	Nitroterephthalic acid modified Polyethylene Glycol	G35	InertCap FFAP

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